@Getty Images
@Getty Images

Study finds cancer mapping may solve puzzle of regional disease links

Embargoed until: Publicly released:
Peer-reviewed: This work was reviewed and scrutinised by relevant independent experts.

Meta-analysis: This type of study involves using statistics to combine the data from multiple previous studies to give an overall result. The reliability of a meta-analysis depends on both the quality and similarity of the individual studies being grouped together.

Simulation/modelling: This type of study uses a computer simulation or mathematical model to predict an outcome. The original values put into the model may have come from real-world measurements (eg: past spread of a disease used to model its future spread).

People: This is a study based on research using people.

QUT researchers have used nationwide cancer mapping statistics to develop a new mathematical model so health professionals can further question patterns relating to the disease.

Journal/conference: Royal Society Open Science

Research: Paper

Organisation/s: Queensland University of Technology (QUT)

Funder: The author(s) disclosed receipt of the following financial support for the research, authorship and/or publication of this article. This work was supported by Decision Making in the Big Data Era under grant no. FL150100150.

Media release

From: Queensland University of Technology (QUT)

Epidemiologists use disease atlases to identify disease prevalence and mortality rates and QUT researchers say data could be expanded by including factors such as remoteness to investigate health inequalities.

QUT PhD student Farzana Jahan is the lead author of a study, published in the Royal Society Open Science, that used a statistical approach to reveal patterns of cancer incidence according to the “remoteness”.

The study, which drew upon the Australian Cancer Atlas, considered cancers from geographical regions including major cities, inner regional, outer regional and remote areas.

Cancers having higher incidence in remote areas were head and neck, liver, lung, oesophageal for males and females and cervical and uterine cancers for females.

While in major cities, cancers more likely to have greater incidence include brain, myeloma, non-Hodgkin lymphoma, pancreatic, stomach, thyroid cancer for both sexes, kidney cancer for males, leukaemia, and ovarian cancer for females.

Some cancers more likely to occur in regional areas included bowel, melanoma for both males and females, kidney cancer for females, leukaemia, and prostate cancer for males.

Ms Jahan said the research was an attempt to create a method by which any available disease maps or summary disease measures can be further modelled to “unmask new insights about health and medical issues” without having to go back to the individual health records.

“Our research provides a method for further analysing information that goes beyond the scope of disease summaries,” Ms Jahan said.

Dr Susanna Cramb, a biostatistician and epidemiologist based at QUT’s Faculty of Health and who co-authored the study, said disease atlases are helpful for showing patterns but rarely adjusted for anything beyond age and population size.

“People might be interested in considering whether for instance the distance to the nearest radiotherapy facility affects survival, or the proportion of workers with high sun exposure is associated with melanoma incidence,” Dr Cramb said.

“Comparing socioeconomic associations with certain cancer types and with other countries worldwide is another potential area to investigate.

“This study unlocks data from sources like the Cancer Atlas to explore and refine research hypotheses.”

Other researchers involved with the study included QUT Distinguished Professor Kerrie Mengersen, who is also Deputy Director of the ARC Centre of Excellence for Mathematical and Statistical Frontiers (ACEMS) based at QUT, Dr Earl Duncan and Professor Peter Baade from Cancer Council Queensland.

Attachments:

Note: Not all attachments are visible to the general public

  • Queensland University of Technology (QUT)
    Web page

News for:

Australia
QLD

Media contact details for this story are only visible to registered journalists.