Image by Crustina from Pixabay
Image by Crustina from Pixabay

Reanimating a heart after death for organ transplant

Embargoed until: Publicly released:
Peer-reviewed: This work was reviewed and scrutinised by relevant independent experts.

Case study: A study involving observations of a single patient or group of patients.

People: This is a study based on research using people.

Two US studies describe two different methods of preserving donated hearts, which might increase the availability of heart transplants. In one study, researchers 'reanimated'  a heart on the operating table, getting it to beat again after it was removed from a paediatric donor. The team set up a device made from pumps, bags and an oxygenator, that could keep blood flowing through the heart after it was removed from the donor. The heart was successfully implanted into a 3-month-old baby. The second study involved three cases in which surgeons flushed the hearts with a cold-preserving liquid before their removal from donors. This allowed the hearts to be transplanted without the ethical complications of 'reanimating' them using machines that restart the donor's blood circulation.

Journal/conference: New England Journal of Medicine

Research: Link to Paper 1 | Paper 2

Organisation/s: Duke University Medical Center, USA, Vanderbilt University Medical Center, USA

Funder: Sere papers for funding information.

Attachments:

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  • Massachusetts Medical Society
    Web page
    Paper 1 - Please link to the article in online versions of your report (the URL will go live after the embargo ends).
  • Massachusetts Medical Society
    Web page
    Paper 2 - Please link to the article in online versions of your report (the URL will go live after the embargo ends).

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