Real world data suggests mRNA COVID vaccines are 91% effective

Embargoed until: Publicly released:
Peer-reviewed: This work was reviewed and scrutinised by relevant independent experts.

Observational study: A study in which the subject is observed to see if there is a relationship between two or more things (eg: the consumption of diet drinks and obesity). Observational studies cannot prove that one thing causes another, only that they are linked.

People: This is a study based on research using people.

A study of almost 4000 frontline workers has found the mRNA COVID vaccines made by Pfizer and Moderna are 91 per cent effective after two doses, they were also found to reduce the viral RNA load, and shorten the duration of illness if the breakthrough infection did occur. The US study recorded 204 COVID-19 infections, of which five were in those fully vaccinated, 11 were in people partially vaccinated, and 156 were in unvaccinated people (32 were in people with indeterminate vaccination status). For those that still got infected the study found that the risk of fever was lower and vaccinated people spent 2.3 fewer sick days spent in bed.

Journal/conference: New England Journal of Medicine

Link to research (DOI): 10.1056/NEJMoa2107058

Organisation/s: Centers for Disease Control and Prevention, USA

Funder: Funded by the National Center for Immunization and Respiratory Diseases and the Centers for Disease Control and Prevention.

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