EXPERT REACTION: First baby born using 'three person IVF' to treat mitochondrial disease
The first baby conceived using DNA from 3 people in order to prevent mitochondrial disease has been born in Mexico, according to research to be presented at the American Society of Reproductive Medicine (ASRM) conference. The five month old baby boy was conceived using a technique known as spindle nuclear transfer, where the nucleus of the mother's egg is transplanted into a donor egg with healthy mitochondria which has had its own nucleus removed. Because mitochondria have their own small amount of DNA, once the egg is fertilised via IVF, the embryo contains the genetic material from three different people. The technique was used in order to try and stop the baby developing the mitochondrial disease known as Leigh Syndrome. In Australia this type of technique is not permitted under the current legislation.
Organisation/s: Australian Science Media Centre, Monash University, The University of Sydney
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Expert Reaction
These comments have been collated by the Science Media Centre to provide a variety of expert perspectives on this issue. Feel free to use these quotes in your stories. Views expressed are the personal opinions of the experts named. They do not represent the views of the SMC or any other organisation unless specifically stated.
Professor Justin St John is Professor and Head of the Centre for Genetic Diseases at the Hudson Institute of Medical Research, Monash University