Photo by Angiola Harry on Unsplash
Photo by Angiola Harry on Unsplash

Breast cancer survival linked to reduced Alzheimer's risk

Embargoed until: Publicly released:
Peer-reviewed: This work was reviewed and scrutinised by relevant independent experts.

Observational study: A study in which the subject is observed to see if there is a relationship between two or more things (eg: the consumption of diet drinks and obesity). Observational studies cannot prove that one thing causes another, only that they are linked.

People: This is a study based on research using people.

Breast cancer survivors may be less likely to develop Alzheimer's in the years after surgery, according to international research. To investigate concerns around loss of brain function after cancer, the researchers took data on 70,000 Korean breast cancer surgery patients and compared it with about 140,000 people of a similar demographic who did not have breast cancer, following up for an average of just over seven years. The researchers say the breast cancer survivors were slightly less likely to develop Alzheimer's during the study, with this reduced risk only apparent in the first five years of cancer survival. The researchers say it's possible certain cancer treatments have some sort of impact on Alzheimer's risk.

Journal/conference: JAMA Network Open

Research: Paper

Organisation/s: Seoul National University College of Medicine, South Korea

Funder: None reported.

Media release

From: JAMA

About The Study: This cohort study of breast cancer survivors found a lower risk of Alzheimer dementia (AD) compared with cancer-free controls, despite common concerns about cognitive decline after treatment. The findings suggest certain cancer treatments potentially have benefits for lower AD risk. Further research is needed to assess the long-term risk of AD in this population.

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