A healthier heart during pregnancy may mean a healthier pre-teen child
Embargoed until:
Publicly released:
2021-02-17 03:00
A US study of more than 2,000 mums and their early adolescent kids in six countries found mums who had better heart health while pregnant had healthier children. Mums' heart health during pregnancy was measured by looking at their body mass index (BMI), blood pressure, cholesterol, blood sugar, and whether or not they smoked. The kids' health was measured in the same way, although their average age was around 11 when measurements were taken, so smoking was not included. This type of study cannot show that mum's poor heart health during pregnancy actually caused poorer heart health in her child at around age 11, just that children of less healthy mums-to-be tended to be less healthy themselves.
Journal/conference: JAMA
Link to research (DOI): 10.1001/jama.2021.0247
Organisation/s: Northwestern University, USA
Funder: The HAPO Study was funded by
grants R01HD34242 and R01HD34243 from the
Eunice Kennedy Shriver National Institute of Child
Health and Human Development, with additional
HAPO ancillary study data obtained through grants
R01DK095963 and R01DK117491 from the National
Institute of Diabetes and Digestive and Kidney
Diseases. The HAPO Follow-Up Study was funded
by grant 1U01DK094830 from the National
Institute of Diabetes and Digestive and Kidney
Diseases and the Eunice Kennedy Shriver National
Institute of Child Health and Human Development.
The ancillary cardiovascular health study was
funded by a Dixon Translational Research Grant from the Northwestern University Clinical and
Translational Sciences Institute and the
Northwestern Memorial Foundation, an Eleanor
Wood-Prince Grant from theWoman’s Board of
Northwestern Memorial Hospital, and a
subcontract under grant 17SFRN33660752 from
the American Heart Association. The research
reported in this article was supported, in part, by
grant UL1TR001422 from the National Center for
Advancing Translational Sciences, NIH. Dr Perak’s
work was supported by grant K23HL145101 from
the National Heart, Lung, and Blood Institute and a
Pediatric Physician-Scientist Research Award from
the Northwestern University Feinberg School of
Medicine Department of Pediatrics. The authors’
work was also supported in part by grants
17SFRN33660752 (Dr Labarthe), 17SFRN33700101
(Drs Labarthe, Allen, and Lloyd-Jones), and
17SFRN33700155 (Dr Shah) from the American
Heart Association.
Media release
From: JAMA
Association of Maternal Cardiovascular Health During Pregnancy With Later Health of Offspring in Adolescence
What The Study Did: The observational study examined associations between maternal cardiovascular health during pregnancy (as measured by body mass index, blood pressure, total cholesterol level, glucose level and smoking) with the later cardiovascular health of their offspring at ages 10 to 14 years old (as measured by body mass index, blood pressure, total cholesterol level and glucose level).
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