Photo by Tanaphong Toochinda on Unsplash
Photo by Tanaphong Toochinda on Unsplash

Exposing small amounts of allergens to kids in early childhood could be better than avoiding them

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Peer-reviewed: This work was reviewed and scrutinised by relevant independent experts.

Systematic review: This type of study is a structured approach to reviewing all the evidence to answer a specific question. It can include a meta-analysis which is a statistical method of combining the data from multiple studies to get an overall result.

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Exposing young children to small amounts of the foods they’re allergic to could be safer than avoiding the foods altogether, according to a review by international researchers who say avoiding the foods could be very dangerous if accidental exposure occurs. The review notes that exposing preschool aged kids to small amounts of food allergens – known as oral immunotherapy – can lessen the severity of a reaction following an accidental exposure. Delaying this therapy to a later age also misses a window of opportunity when it’s the safest, the team says, adding that after avoiding allergens as a child, sometimes people grow out of it but continue to avoid the triggering foods, and increase the chance of redeveloping the allergy.

Journal/conference: Clinical & Experimental Allergy

Research: Paper

Organisation/s: University of British Columbia, Canada

Funder: The authors received no specific funding for this work.

Media release

From: Wiley

Review supports introducing small amounts of food allergens during early childhood

A review in Clinical & Experimental Allergy concludes that exposing young children to small amounts of foods that they’re allergic to is safer than avoiding the foods altogether, which could be very dangerous if accidental exposure occurs.

The review notes that exposing preschool-aged children to small amounts of food allergens—called oral immunotherapy—can lessen the severity of a reaction following an accidental exposure. Also, delaying exposure until a later age misses the window of opportunity when oral immunotherapy is safest, and it prolongs unnecessary dietary restrictions. Also, after early childhood avoidance, some people who outgrow their allergy will not reincorporate the food into their diet due to fear and anxiety, thus potentially increasing their chance of redeveloping the allergy.

A growing body of evidence indicates that oral immunotherapy is safe and effective in preschoolers, but additional research is needed to clarify its impact on children’s health and quality of life.

“This research highlights a critical shift in how we approach food allergies—moving from strict avoidance to controlled exposure in early childhood, which not only reduces the risk of severe reactions but also helps prevent long-term negative consequences of living with food allergies,” said corresponding author Lianne Soller, PhD, of the University of British Columbia, in Canada.

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