The maximum safe dose of ivermectin still doesn't help treat COVID-19

Embargoed until: Publicly released: 2023-02-21 10:15

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Taking the highest possible safe dose of ivermectin does not help treat mild to moderate COVID-19, according to international research. The researchers randomly assigned 600 people with mild to moderate symptomatic COVID-19 to receive 600 micrograms per kilogram of ivermectin, and 600 were given a placebo for six days. The researchers say there was no improvement in how quickly the ivermectin group recovered compared to the placebo group, meaning the highest dose that humans can safely tolerate is not effective to treat COVID-19.

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Journal/
conference: JAMA

Research:Paper

Organisation/s: Duke University, USA

Funder: ACTIV-6 is funded by the NCATS (3U24TR001608-06S1). Additional support for this study was provided by the Office of the Assistant Secretary for Preparedness and Response, Biomedical Advanced Research and Development Authority (contract No.75A50122C00037). The Vanderbilt University Medical Center Clinical and Translational Science Award from NCATS (UL1TR002243) supported the REDCap infrastructure.

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