Moderna's 'COVID arm' not a serious reaction

Embargoed until: Publicly released: 2021-05-13 14:00

International

Figure 1. Delayed Localized Cutaneous Hypersensitivity Reactions After the Moderna Coronavirus Disease 2019 Vaccine: Patient with annular pink plaque and patient with edematous pink plaques. CREDIT: Little, et al (JAMA)

The Moderna COVID-19 vaccine may cause a small hypersensitivity reaction at the site of the injection seven days after administration, according to international researchers who say the reaction is not serious and should not be a reason to avoid the vaccine. The team looked at 16 patients who received the vaccine, and found most of them had itchy, swollen and sore skin at the site of injection seven days after vaccination and could last up to 21 days. Skin biopsies found these reactions are not serious like immediate reactions experienced by those with severe allergic reactions, and should not be a reason to avoid a second dose of Moderna.

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Journal/
conference: JAMA Dermatology

Research:Paper

Organisation/s: Yale University School of Medicine, USA

Funder: Conflict of Interest Disclosures: Dr Little reported a grant from the National Center for Advancing Translational Science (CTSA No. KL2 TR001862), which is a component of the National Institutes of Health, and aWomen’s Health Career Development Award from the Dermatology Foundation during the conduct of the study. DrWatsky reported equity in Johnson & Johnson held by his spouse’s retirement fund outside the submitted work. No other disclosures were reported.

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