Mix-and-match COVID-19 vaccines could be more effective

Embargoed until: Publicly released: 2021-10-22 10:30

International

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Having a first dose of the AstraZeneca vaccine and a second dose of the Pfizer could halve your risk of COVID-19 infection compared to two Pfizer doses, according to an international study. Following a group of people who received one dose of AstraZeneca in Europe, then switched to Pfizer after blood clot concerns came to light, the researchers say 0.4 per cent of these people became infected after their vaccines, compared to 0.76 per cent of people in the study who had two Pfizer vaccines. The researchers say a study of the participants' antibodies showed stronger responses from those who had received both types of vaccine.

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Journal/
conference: Nature

Research:Paper

Organisation/s: Université Claude Bernard Lyon, France

Funder: This study was supported by IDEX Lyon (HPI-2019) operated by the French National Research Agency (ANR-11-IDEX-0007), Inserm-Transfert, and institutional grants from INSERM, CNRS, UCBL1, and ENS de Lyon

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