In this cohort study, childhood loneliness was associated with cognitive decline and dementia risk in middle and later adulthood, even in the absence of adult loneliness. Early interventions aimed at reducing childhood loneliness may help promote lifelong cognitive health and reducing dementia risk.
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conference: JAMA Network Open
conference: JAMA Network Open
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Capital Medical University, China
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This research was funded by the National Natural Science Foundation of China (grant No. 82373683; Dr Guo) and the Capital’s Funds for Health Improvement and Research (grant No. CFH 2024-1G-4261; Dr Guo). The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.