Taking aspirin to prevent heart attack and stroke should be personal choice for ages 40-59, experts say

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Photo by Towfiqu barbhuiya on Unsplash
Photo by Towfiqu barbhuiya on Unsplash

Middle-aged adults should decide for themselves if they want to take a small amount of aspirin daily to possibly reduce their risk of heart attack and stroke, the US Preventive Services Task Force now recommends. However these disease prevention experts advise against low-dose aspirin for those aged 60-plus. There is some evidence that the medication – which blocks clotting but can cause bleeding – can reduce the risk of cardiovascular disease. A linked editorial calls the history of aspirin recommendation 'tortuous', as the taskforce's position has been revised many times as new evidence comes to light.

Media release

From: JAMA

The U.S. Preventive Services Task Force (USPSTF) has updated and changed its recommendation on low-dose aspirin use to prevent cardiovascular disease (CVD). The USPSTF now recommends against initiating low-dose aspirin use for the primary prevention of CVD in adults 60 years or older. The decision to initiate low-dose aspirin use for the primary prevention of CVD in adults ages 40 to 59 years who have a 10% or greater 10-year CVD risk should be an individual one. Evidence indicates that the net benefit of aspirin use in this group is small. Those who are not at increased risk for bleeding and are willing to take low-dose aspirin daily are more likely to benefit. The USPSTF also has concluded the evidence is unclear whether aspirin use reduces the risk of colorectal cancer incidence or death. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this recommendation replaces the 2016 USPSTF recommendation on aspirin use to prevent CVD and colorectal cancer.

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Organisation/s: U.S. Preventive Services Task Force (USPSTF)
Funder: The USPSTF is an independent, voluntary body. The US Congress mandates that the Agency for Healthcare Research and Quality (AHRQ) support the operations of the USPSTF. AHRQ staff assisted in the following: development and review of the research plan, commission of the systematic evidence review from an Evidence-based Practice Center, coordination of expert review and public comment of the draft evidence report and draft recommendation statement, and the writing and preparation of the final recommendation statement and its submission for publication. AHRQ staff had no role in the approval of the final recommendation statement or the decision to submit for publication.
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