Strongest evidence yet shows safety of COVID-19 vaccines in pregnancy

Embargoed until: Publicly released: 2022-03-25 02:00

International

Two studies looking at more than 250,000 pregnancies from three countries have provided the strongest evidence to date of the safety of COVID-19 vaccines in pregnancy. The studies both found that there was no link between vaccination against COVID-19 and adverse pregnancy outcomes, including still birth, preterm birth or neonatal intensive care. Both studies mostly looked at mRNA vaccinations given in the second and third trimesters. An accompanying editorial says the studies are extremely reassuring and provide the strongest evidence to date that COVID-19 vaccines are safe during pregnancy.

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Research JAMA, Web page Paper 1 - Please link to the article in online versions of your report (the URL will go live after the embargo ends).

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Journal/
conference: JAMA

Research:Paper

Organisation/s: Children’s Hospital of Eastern Ontario (CHEO) Research Institute, Canada, Norwegian Institute of Public Health, Norway

Funder: Study 1 - This study was supported by funding from the Public Health Agency of Canada, through the Vaccine Surveillance Reference Group and the COVID-19 Immunity Task Force. Dr Håberg was partly funded by the Norwegian Research Council (project numbers 324312 and 262700). Study 2 - This research was supported by the Research Council of Norway (project No. 324312) through its Centres of Excellence funding scheme (project No. 262700) and by NordForsk (project No. 105545). Dr Magnus received funding from the European Research Council under the European Union’s Horizon 2020 research and innovation programme (grant No. 947684).

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