Stress may not be the reason you can't stop binge-eating

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While people who binge-eat can lose control of their eating after stressful events, a study by UK and US researchers has concluded stress itself is not the trigger for binge-eating. The study monitored the brain activity of a group of women, including those with bulimia and anorexia, as their ability to stop what they were doing or about to do was tested during both stress and relaxation. While the brain activity of the women with eating disorders was affected by the stress it did not prevent them from completing the task, indicating stress alone does not prevent inhibitory control.

Media release

From: Society for Neuroscience

Binge-Eating Is Not Caused by Stress-Induced Impulsivity

Stress alters brain activity in inhibition network but doesn’t prompt binge-eating, contrary to theory

Stress alters brain activity in self-inhibition areas yet doesn’t trigger binge-eating, according to new research published in JNeurosci.

People who binge-eat, a hallmark symptom of several eating disorders, can feel out of control and unable to stop, and often binge after stressful events. This led scientists to theorize stress impairs the brain regions responsible for inhibitory control — the ability to stop what you are about to do or currently doing — and triggers binge-eating.

Westwater et al. tested this theory by using fMRI to measure the brain activity of women with anorexia, bulimia, or without an eating disorder as they completed an inhibitory control task, either while stressed or relaxed. The task entailed pushing a button to stop a moving bar when it reached a specific point on the screen. On some trials the bar stopped early, and the participants had to prevent themselves from pushing the button. Stress altered the brain activity associated with inhibitory control in both groups of women with eating disorders but had no effect on task performance — meaning they still had the ability to stop their actions. These results indicate self-inhibition is preserved in the face of stress, so the actual mechanism behind binge-eating is more complex than previously thought.

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The Journal of Neuroscience
Research:Paper
Organisation/s: University of Cambridge, UK
Funder: Funding was provided by the Bernard Wolfe Health Neuroscience Fund to PCF and HZ and a Wellcome Trust Investigator Award to PCF (Reference No. 49 206368/Z/17/Z). MLW was supported through the NIH-Oxford-Cambridge Scholars Program and a Cambridge Trust fellowship. FM was supported by research grants from Versus Arthritis, the Experimental Psychological Society and a Career Development Award from the Medical Research Council (MR/T010614/1). AG, CG and ME were supported by the Intramural Research Program of the NIMH (Ref. ZIAMH002798). The Wellcome Trust/NIHR Clinical and Translational Research Facilities and the Wolfson Brain Imaging Centre provided equipment and support staff for the study.
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