Smoking and drinking likely causes of age-related blindness

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Smoking and drinking alcohol are likely to increase your risks of developing age-related macular degeneration, the leading cause of blindness in Australia. The UK based study used a technique called ‘Mendelian Randomisation’ - which uses genetics to allow scientists to look at whether one thing likely causes another, rather than them just being linked. It showed that it is likely that alcohol consumption causes an increased risk of advanced age-related macular degeneration. It also showed that is likely that smoking plays a role in causing advanced age-related macular degeneration but quitting was also likely to lower your risk. 

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Journal/
conference:
JAMA Ophthalmology
Research:Paper
Organisation/s: University College London, UK
Funder: Dr Kuan is funded by the Dunhill Medical Trust (RPGF1806\67). DrWarwick is supported by theWellcome Trust (220558/Z/20/ Z). Dr Hingorani is supported by a BHF Research Accelerator Award (AA/18/6/34223). Dr Tufail is supported by the National Institute for Health Research to Moorfields Eye Hospital and the Biomedical Research Centre for Ophthalmology. Dr Burgess is supported by Sir Henry Dale Fellowship, jointly funded by theWellcome Trust and the Royal Society (204623/Z/16/Z) Dr Sofat is supported by the National Institute for Health Research, University College London Hospitals Biomedical Research Centre. This research was supported by the NIHR Cambridge Biomedical Research Centre (BRC-1215-20014).
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