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Journal/
conference: PLOS Medicine
conference: PLOS Medicine
Research:Paper
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Baker Heart and Diabetes Institute, University of Cambridge, UK
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This work was supported by core funding
from the UK Medical Research Council (MR/
L003120/1), the British Heart Foundation (RG/13/
13/30194; RG/18/13/33946), and the National
Institute for Health Research (NIHR) (Cambridge
Biomedical Research Centre at the Cambridge
University Hospitals NHS Foundation Trust). This
work was supported by Health Data Research UK,
which is funded by the the UK Medical Research
Council, the Engineering and Physical Sciences
Research Council, the Economic and Social
Research Council, the Department of Health and
Social Care (England), the Chief Scientist Office of
the Scottish Government Health and Social Care
Directorates, the Health and Social Care Research
and Development Division (Welsh Government),
the Public Health Agency (Northern Ireland), the
British Heart Foundation, and Wellcome. Luanluan
Sun, Lisa Pennells, Stephen Kaptoge, and Matthew
Arnold are funded by a British Heart Foundation
Programme Grant (RG/18/13/33946). Scott
Ritchie, Mike Inouye, and Stephen Burgess are
funded by the National Institute for Health
Research (Cambridge Biomedical Research Centre
at the Cambridge University Hospitals NHS
Foundation Trust). David Stevens was funded by
the National Institute for Health Research
(Cambridge Biomedical Research Centre at the
Cambridge University Hospitals NHS Foundation
Trust). Thomas Bolton is funded by the NIHR
Blood and Transplant Research Unit in Donor
Health and Genomics (NIHR BTRU-2014-10024).
Steven Bell was funded by the NIHR Blood and
Transplant Research Unit in Donor Health and
Genomics (NIHR BTRU-2014-10024). Angela
Wood is supported by a BHF-Turing Cardiovascular
Data Science Award and by the EC-Innovative
Medicines Initiative (BigData@Heart). Professor
John Danesh holds a British Heart Foundation
Professorship and a National Institute for Health
Research Senior Investigator Award. See paper for competing interests