Australia; VIC
Immune cells called B-cells from people allergic to peanuts show differences in the control of genes compared to people who are not allergic. Genes are controlled through epigenetics which is essentially additional chemical information layered on top of our DNA to turn genes on and off. The researchers also found that the immune cells of people with allergies to peanuts alone have different epigenetic profiles to people with multiple food allergies that include peanuts. The researchers say there may be different developmental pathways underpinning these allergy types.
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