Media release

From: The Royal Society

Opium alkaloids, biosynthesis, pharmacology and association with cancer occurrence

The study highlights the biosynthetic pathways of alkaloids, which are found in high amount in Papaver somniferum, and are highly effective pain reliever. However, recent investigations have revealed a potential link between opium use and an increased risk of developing various types of cancer which raises concerns about the safety of commonly used pain medications. Opium alkaloids have been found to have both tumour progression as well as tumour inhibition effects, making it difficult to determine their overall impact on cancer development and progression. The potential link between opium use and cancer development is an important topic for public in general to understand, particularly given the widespread use of opium alkaloids for pain management.