Noisy knees not an early arthritis sign in young people, research shows

Publicly released:
Australia; VIC

Young adults who experience grinding or clicking sounds in their knees post-surgery may be alarmed, but new research from La Trobe University suggests these sounds may not signal early-onset osteoarthritis. Knee crepitus, the sound of cracking or grinding in the knee joint is very common across all age groups. The study, published in the Arthritis Care & Research journal, followed 112 young adults after anterior cruciate ligament (ACL) reconstruction, using Magnetic Resonance Imaging (MRI) scans and patient-reported outcomes to track osteoarthritis signs over five years.

Media release

From: La Trobe University

Young adults who experience grinding or clicking sounds in their knees post-surgery may be alarmed, but new research from La Trobe University suggests these sounds may not signal early-onset osteoarthritis.

Knee crepitus, the sound of cracking or grinding in the knee joint is very common across all age groups.

The study, published in the Arthritis Care & Research journal, followed 112 young adults after anterior cruciate ligament (ACL) reconstruction, using Magnetic Resonance Imaging (MRI) scans and patient-reported outcomes to track osteoarthritis signs over five years.

La Trobe graduate researcher and physiotherapist Jamon Couch said that while knee crepitus was linked to cartilage damage and worse symptoms one year after surgery, it did not predict joint damage over time.

“We found that those with knee crepitus demonstrated more than two and a half times greater rates of full-thickness cartilage defects in the kneecap area, with more pain and poorer function early on,” Jamon said.

“But over the next four years, those with crepitus did not experience worse pain and function compared to those without knee crepitus.”

Research shows about 50 per cent of people with an ACL rupture will develop osteoarthritis symptoms and structural changes within a decade of injury, nearly 15 years earlier than the uninjured.

The findings challenge the idea that crepitus should be used to diagnose or predict early osteoarthritis following traumatic knee injury in young adults.

Dr Adam Culvenor, head of the Knee Injury Research Group at La Trobe’s Sport and Exercise Medicine Research Centre (LASEM) said the research would be reassuring for younger patients worried that noisy knees may be a red flag signalling their joint was deteriorating after surgery.

“It also highlights the importance of staying active and engaged in rehabilitation to avoid or delay osteoarthritis,” Dr Culvenor said.

The researchers say the study supports a more nuanced approach to diagnosing early-stage osteoarthritis and encourages health professionals to avoid overinterpreting crepitus in young, active patients.

DOI: doi.org/10.1002/acr.25637

Dr Adam Culvenor and Jamon Couch are available for interview.

Journal/
conference:
Arthritis Care & Research
Research:Paper
Organisation/s: La Trobe University
Funder: This research was supported by Arthritis Australia (Grant in Aid), La Trobe University's Sport,Exercise and Rehabilitation Research Focus Area (Project Grant), the QueenslandOrthopaedic Physiotherapy Network (Project Grant), the University of Melbourne (Research Collaboration Grant), and the University of British Columbia's Centre for Hip Health and Mobility (Society for Mobility and Health). JLC is supported by an Australian GovernmentResearch Training Program scholarship. BEP is supported by an Australian Research Council Early Career Industry Fellowship (IE230100135) and was supported by a National Health and Medical Research Council (NHMRC) of Australia postgraduate scholarship at the time of thestudy (GNT1114296). DOS is supported by an NHMRC of Australia Investigator Grant(GNT2033417). JLW is supported by a Michael Smith Health Research British Columbia Scholar Award (SCH-2020-0403). MAG was supported by an NHMRC of Australiapostgraduate scholarship at the time of the study (GNT1190882). AGC is supported by an NHMRC of Australia Investigator Grant (GNT2008523). The funders had no role in any part of the study or in any decision about publication.
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