No evidence aspirin can prevent fractures from falls in older people

Embargoed until: Publicly released: 2022-11-08 03:00

Australia; NSW; VIC

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A low, regular dose of aspirin does not appear to do anything to reduce the risk of fractures from falls in older people, according to Australian research. Research indicates aspirin can reduce bone fragility and slow bone loss, so researchers gave about 8300 older Australians a low, daily dose and after about 4.6 years, compared the amount of fractures and falls in the group with about 8300 older Australians who didn't take the medication. The researchers say there was no reduced risk of fractures and a small increase in risk of serious falls in the aspirin group, suggesting the drug has no benefit for this purpose.

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Journal/
conference: JAMA Internal Medicine

Research:Paper

Organisation/s: Monash University, The University of Melbourne, The University of New South Wales, The University of Sydney

Funder: This work was supported by the National Institute on Aging and the National Cancer Institute at the National Institutes of Health (U01AG029824, U19AG062682); the NHMRC (334047, 1127060, and APP1067242); Monash University; and the Victorian Cancer Agency. Dr McNeil is supported through an NHMRC Leadership Fellowship (IG 1173690). Dr Hussain is supported by NHMRC Early Career Fellowship (APP1142198). Dr Barker was supported by a NHMRC Career Development Fellowship (APP1067236). ASPREE was additionally supported by the University of Pittsburgh Claude D. Pepper Older American Independence Center (P30 AG024827) and theWake Forest University Claude D. Pepper Older Americans Independence Center (P30AG021332).

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