New and old drugs may help dampen the pain of acute migraines

Embargoed until: Publicly released: 2021-06-16 01:00

International

Aarón Blanco Tejedor

A review of trials has found that older drugs such as common anti-inflammatory drugs, and newer drugs such as monoclonal antibodies, can all help improve pain during an acute migraine, while the evidence for opioids was limited. A second study on the monoclonal antibody eptinezumab, which is used for migraine prevention, also found that when it was given during an acute attack it shortened the time it took to be free from headache pain and migraine symptoms.

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Research JAMA, Web page Trial link - Please link to the article in online versions of your report (the URL will go live after the embargo ends).

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Journal/
conference: JAMA

Research:Paper

Organisation/s: Mayo Clinic Evidence-based Practice Center, USA, Lundbeck La Jolla Research Center, USA

Funder: Paper 1 (review) - This project was funded under contract HHSA290201500013I task order 75Q80119F32007 from the Agency for Healthcare Research and Quality (AHRQ), US Department of Health and Human Services (HHS). Paper 2 - The study was sponsored and funded by H. Lundbeck A/S, including editorial support for the development of the manuscript.

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