It's still ok to vaccinate mums-to-be against the flu

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Photo by CDC on Unsplash
Photo by CDC on Unsplash

Flu vaccinations during pregnancy are not associated with negative outcomes, according to international researchers. The team looked at data from over 82,000 mums with two singleton pregnancies (not twins) between 2004 and 2018. Vaccination was not found to be associated with increased risk of negative birth outcomes, such as preeclampsia or eclampsia, maternal fever, preterm birth, small birthweight and more, when compared to mums who were not vaccinated in both pregnancies. The findings support recommendations to vaccinate pregnant people or those who might become pregnant during the flu season, according to the team.

Media release

From: JAMA

Safety of the Seasonal Influenza Vaccine in 2 Successive Pregnancies

JAMA Network Open
Original Investigation

About The Study: In this large cohort study of successive pregnancies, influenza vaccination was not associated with increased risk of adverse perinatal outcomes, irrespective of interpregnancy interval and vaccine type. Findings support recommendations to vaccinate pregnant people or those who might be pregnant during the influenza season. 

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conference:
JAMA Network Open
Research:Paper
Organisation/s: Kaiser Permanente Southern California, USA
Funder: This research was funded by the Centers for Disease Control and Prevention (CDC) as part of the Vaccine Safety Datalink project (contract No. 200-2012-53580). Conflict of Interest Disclosures: Dr Getahun reported receiving grants from the National Institutes of Health (NIH) Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Garfield Memorial Fund, Hologic, and Johnson & Johnson outside the submitted work. Dr Sy reported receiving grants from Moderna, GlaxoSmithKline, and Dynavax outside the submitted work. Dr Glanz reported receiving grants from Hillivax outside the submitted work. Dr Vazquez-Benitez reported receiving grants from AbbVie and Sanofi Pasteur outside the submitted work. Dr Nelson reported receiving personal fees from Harvard Pilgrim Health Care outside the submittedwork. Dr Nguyen reported receiving grants from CSL Seqirus, ModernaTX, and GSK outside the submittedwork. Dr Qian reported receiving grants from Moderna, GlaxoSmithKline, and Dynavax outside the submitted work. No other disclosures were reported. Role of the Funder/Sponsor: As the funding organization, the CDC reviewed and approved the study protocol, assisted with data collection and interpretation, and contributed to the writing of the manuscript. The CDC had no role in data management or analysis.
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