It may be worth re-engineering UQ's Aussie COVID-19 vaccine to avoid the HIV test issue

Embargoed until: Publicly released: 2021-04-06 05:00

Australia; VIC; QLD

A model of a clamped vaccine antigen. Credit: UQ

The Australian COVID-19 vaccine developed by The University of Queensland was abandoned over concerns it could create false-positive HIV tests, but data from animal trials now shows that it provided good COVID-19 protection and was stable at fridge temperatures. This suggests the underlying platform worked and it may be worth re-engineering it to avoid this HIV issue. The authors say this vaccine has significant advantages that demonstrate the suitability of the underlying platform technology to meet the global response to the ongoing COVID-19 pandemic as well as novel viruses that may emerge in the future.

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Journal/
conference: Clinical & Translational Immunology

Research:Paper

Organisation/s: The University of Queensland, Doherty Institute for Infection and Immunity, The University of Melbourne, The Australian National University, CSIRO

Funder: This work was funded by CEPI.

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