Man's best friend could help stop a real pain in the back

Embargoed until: Publicly released: 2025-05-28 09:01

International

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Analysis of the spines of dogs could provide insights into ‘slipped-disc’ disease in humans, according to international researchers. The team looked at around 100 herniated and non-herniated discs (which are the cartilage pads between vertebrae) from dogs following surgery. They found mineral changes within the herniated discs that may make them more likely to rupture. More research is needed, but the researchers say investigating this process may point to new therapies or preventative measures for slipped discs in humans (and dogs).

Media release

From: The Royal Society

Mineral Phase Changes During Intervertebral Disc Degeneration

Proceedings of the Royal Society A: Mathematical and Physical Sciences

This novel study identifies a previously unknown mechanism for intervertebral disc degeneration and calcification in dogs which may have significant ramifications in human 'slipped disc' disease. We have shown that the process of disc disease likely involves a conversion of amorphous calcium phosphate into a crystalline form of calcium phosphate and that this potentially predisposes the disc to herniate. Interference with this process may help to prevent slipped discs in dogs and people.

Journal/
conference: Proceedings of the Royal Society A

Research:Paper

Organisation/s: University of Cambridge, UK

Funder: The authors received no funding for this study.

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