How does COVID-19 impact the placenta and lead to a 'pre-eclampsia-like sydrome' ?

Embargoed until: Publicly released: 2024-02-07 03:00

Australia; NSW; QLD

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For some women, having COVID-19 during pregnancy can impact their placenta and lead to a ‘preeclampsia-like syndrome’, and now Australian experts have identified some of the changes taking place in the placenta that might explain this syndrome. The researchers found that the products of genes linked to blood pressure, preeclampsia, and inflammation are increased in the placenta of women who contracted the virus in the third trimester of their pregnancy.

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Journal/
conference: Clinical & Translational Immunology

Research:Paper

Organisation/s: Queensland University of Technology (QUT), The University of Queensland, Bond University, University of Technology Sydney (UTS)

Funder: This study was funded by the Queensland University of Technology ECR funds for AK, JR, MA, NS. The following authors are supported by fellowships from the NHMRC (AK – 1157741, GB – 2008542 and 1135898) and US Department of Defense (NS – PC190533). The authors thank Fred Hutchinson Pathology (Miki Haraguchi & Stephanie Weaver) for histology assistance. Open access publishing facilitated by The University of Queensland, as part of the Wiley - The University of Queensland agreement via the Council of Australian University Librarians.

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