Genetic testing could pick up prostate cancer that screening might miss

Embargoed until: Publicly released: 2025-04-10 07:00

Australia; International; VIC

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DNA testing to pick up men in the top 10% of genetic prostate cancer risk could help detect cases of prostate cancer that other screening might miss, according to international and Australian research. The study found that when men with a genetic risk score in the top 10% were invited to undergo further testing, prostate cancer was detected in about 40% of cases, and around half of these cases met the criteria for treatment. The research also found that this cancer would not have been found with current UK screening guidelines in about 72% of cases.

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Editorial / Opinion Massachusetts Medical Society, Web page Please link to the article in online versions of your report (the URL will go live after the embargo ends).

Journal/
conference: New England Journal of Medicine

Research:Paper

Organisation/s: The University of Melbourne, Institute of Cancer Research, UK

Funder: Funded by the European Research Council Seventh Framework Program and others; BARCODE1 ClinicalTrials.gov number, NCT03857477

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