Genes point to causes of a common age related blood condition

Publicly released:
Australia; VIC

Australian and international researchers have looked at what might be causing a common condition of aging that affects about 10% of healthy people over 65 years old, known as clonal haematopoiesis (CH). People with this condition develop mutations in their blood cells which can put them at higher risk of developing blood cancers and other conditions, but it has not been clear why these mutations occur in some people but not others. The researchers have shown that if people's white blood cells have longer sections at the end of their chromosomes, known as telomeres, they are more at risk of CH. They have also found that smoking can cause CH and that having a genetic predisposition to CH can also put you at higher risk of cancer and irregular heartbeat.

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Research Springer Nature, Web page Please link to the article in online versions of your report (the URL will go live after the embargo ends).
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conference:
Nature Genetics
Research:Paper
Organisation/s: The University of Melbourne, University of Bristol, UK
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