Early-life mental disorders linked to dementia

Publicly released:
New Zealand
 Nick Karvounis on Unsplash
Nick Karvounis on Unsplash

People with mental disorders are at higher risk of developing dementia, finds a massive longitudinal study which looked at the health data of a third of New Zealand's population over three decades. The increased risk is stronger for mental disorders than physical diseases, and on par with the strongest risk factor gene for Alzheimer's disease – the APOE4 allele. The researchers say this suggests treating mental disorders early in life might help prevent later cognitive decline.

Media release

From:

Association of Mental Disorders With Dementia

What The Study Did: Researchers examined whether mental disorders were associated with the onset of dementia in this study of 1.7 million New Zealand citizens across three decades of observation.

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Journal/
conference:
JAMA Psychiatry
Research:Paper
Organisation/s: University of Auckland
Funder: This research was supported by grants AG032282, AG069939, and AG049789 from the National Institute on Aging; grant MR/ P005918/1 from the UK Medical Research Council; grant P2C HD065563 from the National Institute of Child Health and Development through the Duke Population Research Center; and grant P30 AG066589 from the National Institute on Aging through the Center for Advancing Sociodemographic and Economic Study of Alzheimer’s Disease and Related Dementias
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