Drug designed to prevent cerebral palsy in preterm babies may not work past 30 weeks

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Australia; New Zealand; SA

A drug called magnesium sulphate doesn't appear to improve the likelihood of having a child without cerebral palsy when given to mothers at risk of imminent preterm birth between the 30th and 34th weeks of pregnancy,  according to Australian research.  While previous studies have shown the drug improves the chances of preterm babies surviving without cerebral palsy, how well it works for very premature babies compared to those born at around the 30-34 week mark was unclear. This study suggests there was no benefit for children born between 30 and 34 weeks gestation. The authors say the ways that brain injuries lead to cerebral palsy may be different in very premature babies compared with those born at later gestational ages.

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Research JAMA, Web page Please link to the article in online versions of your report (the URL will go live after the embargo ends).
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JAMA
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Organisation/s: University of Auckland, The University of Adelaide, South Australian Health and Medical Research Institute (SAHMRI), University of Technology Sydney (UTS)
Funder: This trial was funded by grant 1022968 from the National Health and Medical Research Council in Australia and grants PG5716 and PG01817 from the Cerebral Palsy Alliance Research Foundation Australia.
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