Pfizer's COVID-19 pill Paxlovid reduces risk of severe disease

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Photo by Volodymyr Hryshchenko on Unsplash
Photo by Volodymyr Hryshchenko on Unsplash

Pfizer's Paxlovid pill reduces the risk of symptomatic COVID-19 progressing to severe disease by 89 per cent, according to the company's phase 2-3 trial. Paxlovid contains the drug Nirmatrelvir with Ritonavir acting as an enhancer. The study saw 2246 non-hospitalised COVID-19 patients at risk of developing severe COVID-19 assigned to either receive a course of the pill or a placebo. Comparing the rates of severe COVID-19 in the two groups, the researchers say significantly fewer people who received the treatment were hospitalised, and all 13 deaths were in the placebo group.

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New England Journal of Medicine
Research:Paper
Organisation/s: Pfizer, USA
Funder: Supported by Pfizer; ClinicalTrials.gov number, NCT04960202.
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