Catching the wrong kind of break: midlife women with prediabetes at risk of fractures

Embargoed until: Publicly released: 2023-05-24 01:00

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Women with prediabetes who are reaching midlife might have a much higher risk of breaking a bone during their shift to menopause and onward, say US researchers, compared to women who didn't have the condition. The team say that of the nearly 1700 women they studied, those with prediabetes had a 120% higher risk of a fracture in later life than their peers, and this association was independent of bone mineral density.

Media release

From: JAMA

About The Study: The findings in this study of nearly 1,700 midlife women without diabetes suggest that prediabetes was associated with risk of fracture. Future research should determine whether treating prediabetes reduces fracture risk.

Journal/
conference: JAMA Network Open

Research:Paper

Organisation/s: David Geffen School of Medicine at University of California, Los Angeles, USA

Funder: The Study of Women’s Health Across the Nation is supported by grants U01NR004061, U01AG012505, U01AG012535, U01AG012531, U01AG012539, U01AG012546, U01AG012553, U01AG012495, and U19AG063720 from the National Institutes of Health (NIH), US Department of Health and Human Services, through the National Institute on Aging (NIA), the National Institute of Nursing Research (NINR), and the NIH Office of Research onWomen’s Health (ORWH). Role of the Funder/Sponsor: The funding sources had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

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