Antibody combo shows promise for hard to treat cancers

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Image by PDPics from Pixabay
Image by PDPics from Pixabay

A combination of two antibodies which target and boost the immune system, have shown promising results against hard to treat solid tumours in an early-stage clinical trial. The drugs, called CS1002 and CS1003 (or nofazinlimab), were trialled in patients with multiple types of cancer, including melanoma, lung cancer and liver cancer.  The trial which was split into three parts, found that of the 61 patients who received the drug in the third stage, 37.7% had a positive response. The study also found the drugs had a manageable safety profile. The authors say this early trial supports further assessment of the combination of drugs for the treatment of solid tumours.

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Journal/
conference:
CANCER
Research:Paper
Organisation/s: The University of Adelaide, The Alfred, Southern Medical Day Care Centre, The Kinghorn Cancer Centre, Box Hill Hospital, Albury‐Wodonga Regional Cancer Centre, Orange Health Service, CStone Pharmaceuticals
Funder: This study was funded by CStone Pharmaceuticals, Aus Pty, Ltd, Sydney, Australia and CStone Pharmaceuticals (Suzhou) Co, Ltd, Suzhou, China
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