A family history of depression could impact your brain function

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Photo by Tyler Nix on Unsplash
Photo by Tyler Nix on Unsplash

A family history of depression could be linked to lower cognitive performance in the next generation, according to UK research. The study included over 57 000 people and found that for younger people (age range, 6 to 42 years), a family history of depression was linked to worse memory, although there were indications this could be due to differences in education or other socioeconomic factors. For older people, a family history of depression was linked to worse processing speed, attention, and executive function. The researchers found similar links in people who were genetically predisposed to depression, even if they had never been depressed themselves but had a family history of depression. The authors say, this has important implications for understanding and addressing potentially modifiable risk factors.

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conference:
JAMA Psychiatry
Research:Paper
Organisation/s: University of Glasgow, UK
Funder: This work was supported in part by grant DTF/14/03 from the Scottish Executive Chief Scientist Office (Dr Cullen) and grant R01MH036197 from the National Institute of Mental Health (DrWeissman). Dr L. Lyall is supported by a JMAS Sim Fellowship from the Royal College of Physicians of Edinburgh and a Lord Kelvin Adam Smith Fellowship from the University of Glasgow. Ms MacSweeney is supported by a Mental Health Research UK PhD Studentship. Dr Strawbridge is supported by a UK Research and Innovation Health Data Research-UK Fellowship MR/S003061/1 and a Lord Kelvin Adam Smith Fellowship from the University of Glasgow. Dr van Dijk is funded by National Institute of Mental Health grant K99MH129611 and American Foundation for Suicide Prevention Young Investigator Award YIG-R-001-19.
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