Vaccination before and during pregnancy reduced the risk of severe COVID-19 outcomes

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Photo by John Looy on Unsplash, Story by Rachel McDonald, Australian Science Media Centre
Photo by John Looy on Unsplash, Story by Rachel McDonald, Australian Science Media Centre

Women who had a COVID-19 infection during pregnancy were likely to fare better if they were vaccinated before or during their pregnancy, according to international research. The team compared vaccination status among nearly 20,000 Canadian women who had COVID-19 during pregnancy in the Delta and Omicron eras - looking at whether they were hospitalised, admitted to critical care or had a preterm birth. Compared to vaccinated mums, the researchers say unvaccinated women had almost 2.5 times higher risk of hospitalisation if they had Omicron COVID-19 and just over 3.8 times higher risk with Delta. Critical care admission was 10 times lower for vaccinated mothers, and they had a lower risk of having a preterm birth, the researchers say.

News release

From: JAMA

About The Study: This study found that vaccination against SARS-CoV-2 prior to and during pregnancy, before COVID-19 diagnosis, was associated with a lower risk of severe maternal disease and preterm birth regardless of variant time period.

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JAMA
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Organisation/s: University of British Columbia, Canada
Funder: This project was supported by funding from the Public Health Agency of Canada through the COVID-19 Immunity Task Force (2021-HQ-000100 and 2122-HQ-000436), the Canadian Institutes of Health Research (447634), and the BCWomen’s Health Foundation (89026 7537 RR0001).
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