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Preschoolers with pets have fewer food allergies

Embargoed until: Publicly released:
Peer-reviewed: This work was reviewed and scrutinised by relevant independent experts.

Observational study: A study in which the subject is observed to see if there is a relationship between two or more things (eg: the consumption of diet drinks and obesity). Observational studies cannot prove that one thing causes another, only that they are linked.

People: This is a study based on research using people.

Children exposed to indoor cats and dogs during foetal development and early infancy have fewer food allergies, according to a massive study of more than 66,000 children up to the age of three in Japan. Researchers found that 22% of the children had been exposed to pets during the foetal period, and that those exposed to indoor dogs were significantly less likely to experience egg, milk, and nut allergies, while children exposed to cats were significantly less likely to have egg, wheat, and soybean allergies. Surprisingly, children exposed to hamsters (0.9 percent of the total group studied) had significantly greater incidence of nut allergies.

Journal/conference: PLOS ONE

Link to research (DOI): https://doi.org/10.1371/journal.pone.0282725

Organisation/s: Fukushima Regional Center for the Japan Environment and Children's Study, Fukushima Medical University

Funder: Financial support for this project was provided by the National Research Foundation (NRF) and its African Origins Platform, GENUS (the DSI-NRF Centre of Excellence in Palaeosciences), and the Palaeontological Scientific Trust (PAST). DPG received funding from the European Union’s Horizon Europe research and innovation programme under the Marie Skłodowska-Curie actions (grant agreement: 101060666) when revising the manuscript. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

Media release

From: PLOS

Living with pet cats or dogs is associated with fewer food allergies in young children

Even children exposed before birth, as well as those growing up with indoor pets, had fewer food allergies.

In an analysis of over 65,000 infants from Japan, children exposed to pet cats or indoor dogs during fetal development or early infancy tended to have fewer food allergies compared to other children, according to a study published March 29, 2023 in the open-access journal PLOS ONE by Hisao Okabe from the Fukushima Regional Center for the Japan Environment and Children’s Study, Japan, and colleagues.

Across some high-income countries, more than one in ten children are diagnosed with food allergies, and the incidence of food allergies in children continues to rise. Previous research has suggested a potential link between dog or farm animal exposure in pregnancy and early childhood and the reduction of food allergies.

In this study, Okabe and colleagues used data from the Japan Environment and Children’s Study (a nationwide, prospective birth cohort study) to study 66,215 children for whom data on exposure to various pets and food allergies were available. About 22 percent were exposed to pets during the fetal period (most commonly indoor dogs and cats). Among children exposed to indoor dogs and cats, there was a significantly reduced incidence of food allergies, though there was no significant difference for children in households with outdoor dogs. Children exposed to indoor dogs were significantly less likely to experience egg, milk, and nut allergies specifically; children exposed to cats were significantly less likely to have egg, wheat, and soybean allergies. Perhaps surprisingly, children exposed to hamsters (0.9 percent of the total group studied) had significantly greater incidence of nut allergies. 

The data used here were self-reported (supplemented by medical record data gathered during the first trimester of pregnancy, at delivery, and at the one-month check-up), so relies on the accurate recall of participants. Additionally, this study cannot determine if the link between pet exposure and food allergy incidence is causative. Still, the authors suggest that these results can help guide future research into the mechanisms behind childhood food allergies.

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