New method to detect gastric cancer without an invasive endoscopy

Embargoed until: Publicly released: 2025-07-31 01:00

International

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Detecting gastric cancer, the fifth most common cancer globally, currently requires invasive and expensive endoscopies and often detects the disease at a later stage. A new genetic test, called Destinex, could help make detecting gastric cancer as simple as a blood test, according to international researchers. The test looks for specific genetic signals found in small packages that cells use to communicate with each other, called exosomes. Destinex was able to successfully detect early-stage gastric cancer nearly 97% of the time, and the researchers suggest that it has potential as a more noninvasive option for the identification of gastric cancer.

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Journal/
conference: JAMA Surgery

Research:Paper

Organisation/s: Beckman Research Institute of City of Hope, US

Funder: The present work was supported by the CA72851, CA181572, CA184792, CA187956, CA202797, CA214254, and CA271443 grants from the National Cancer Institute, National Institute of Health, as well as by a grant from the American Gastroenterological Association (AGA) Robert & Sally Funderburg Research Award in Gastric Cancer, and generous support from the Stupid Strong Foundation.

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