HPV jab may help prevent precancerous growths on female genitalia

Publicly released:
International
By Jan Christian @ www.ambrotosphotography.com - Gardasil vaccine and box, CC BY-SA 2.0, https://commons.wikimedia.org/w/index.php?curid=6497417. Story by Dr Joe Milton, Australian Science Media Centre
By Jan Christian @ www.ambrotosphotography.com - Gardasil vaccine and box, CC BY-SA 2.0, https://commons.wikimedia.org/w/index.php?curid=6497417. Story by Dr Joe Milton, Australian Science Media Centre

Women who have had the HPV jab are less likely to encounter high-grade vulvovaginal lesions - precancerous growths on the vulva and vagina - according to Swedish scientists. They looked at the health records of 778,943 Swedish women, around a third of whom (256,353) had been vaccinated with the quadrivalent HPV vaccine, and followed up for between 9.3 and 17 years. During that time, 98 vaccinated women developed high-grade vulvovaginal lesions, compared with 547 unvaccinated women. So, vaccinated women were around a third less likely (37%) to develop lesions than the unvaccinated. They found the HPV jab was most effective in preventing these precancerous growths when it was administered before the age of 17.

News release

From: JAMA

Quadrivalent Human Papillomavirus Vaccine and High-Grade Vulvovaginal Lesions

About The Study: In this study, quadrivalent human papillomavirus (HPV) vaccination was associated with reduced risk of high-grade vulvovaginal lesions, suggesting that expanding vaccination, especially at younger ages, could help prevent high-grade vulvovaginal lesions.

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Journal/
conference:
JAMA Oncology
Research:Paper
Organisation/s: Karolinska Institutet, Sweden
Funder: This work was funded by the Swedish Cancer Society (24 3862 Pj), Swedish Research Council (2023-01809), Swedish Research Council for Health,Working Life andWelfare (2023-01221), Karolinska Institutet Strategic Research Area in Epidemiology and Biostatistics, and European Union’s Horizon 2020 research and innovation programme (874662).
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