Gene therapy can outperform a cochlear implant for children with congenital deafness

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Photo by Alireza Attari on Unsplash
Photo by Alireza Attari on Unsplash

Cochlear implantation is considered the gold standard treatment for children born with hearing loss, however, international research has found a new gene therapy could be more effective. The therapy targets a gene that can cause hearing loss when it mutates, and researchers followed up with 11 young patients who had the therapy, and compared their progress with 61 patients of a similar age who received cochlear implantation. The researchers say the results were similar in both groups after three months, but at six and 12 months, the children who received the gene therapy were performing better at tests measuring their auditory response, understanding of speech over background noise and perception of music.

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Journal/
conference:
JAMA Neurology
Research:Paper
Organisation/s: Fudan University, China
Funder: The study was funded by the National Natural Science Foundation of China (82225014, 82171148, 82192864, 82071048, and 82301301), the National Key Research and Development Program of China (2020YFA0908201, 2020YFA0908203, 2021YFA1101302, and 2023YFC2508405), the Science and Technology Commission of Shanghai Municipality (23J31900100 and 21JC1401000), the Xuhui District Hospital and Site Cooperation Project (23XHYD-05), the Shanghai Municipal Health Commission (20224Z0003), the Shanghai Municipal Education Commission (2023ZKZD12), China Disabled Persons’ Federation Hearing and Speech Program (2022CDPFHS-03), and the Science and Technology Innovation Program of Hunan Province (2023RC4005).
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