Cells from a blind fish with no eyes still respond to light

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Australia; QLD
H. Zell, CC BY-SA 3.0 <https://creativecommons.org/licenses/by-sa/3.0>, via Wikimedia Commons
H. Zell, CC BY-SA 3.0 <https://creativecommons.org/licenses/by-sa/3.0>, via Wikimedia Commons

Cells taken from a blind fish - that has evolved without eyes - are still able to respond to light, according to Australian research. Despite the fact that the Mexican blind cavefish has no eyes, it seems that their cells can still detect light, and they have natural biological clocks within their cells that work on a light–dark cycle. The researchers say that this makes them a valuable tool for studying adaptations to life in the dark.

Media release

From: The Royal Society

Blind Fish Have Cells That See Light

Proceedings of the Royal Society B: Biological Sciences

Summary: While most animals follow daily cycles of the sun, some have adapted to a life in darkness. One such example is the Mexican blind cavefish, an eyeless fish, known for minimal sleep that no longer rely on daily clocks. Studying these fishes remains challenging as they are rare, so we established cell cultures from cavefish and tested its suitability to study the changes to the circadian clock. We found that despite originating from eyeless fish, the cells exhibit direct responsiveness to light and can maintain molecular rhythms, making them a valuable tool for studying adaptations to life in the dark.

Multimedia

Mexican blind cavefish,  Astyanax mexicanus
Mexican blind cavefish, Astyanax mexicanus

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Research The Royal Society, Web page Please link to the article in online versions of your report (the URL will go live after the embargo ends).
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conference:
Proceedings of the Royal Society B
Research:Paper
Organisation/s: James Cook University, Australian Institute of Tropical Health and Medicine (AITHM)
Funder: Medical Research council MR/N013867/1 and Leverhulme Trust grant RPG-2017-299 used for consumables and experimental material.
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