A pill version of the weight-loss and diabetes drug, semaglutide, could benefit people with heart failure

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Photo by Haberdoedas on Unsplash. Story by Lyndal Byford, Australian Science Media Centre
Photo by Haberdoedas on Unsplash. Story by Lyndal Byford, Australian Science Media Centre

Taking the weight loss and diabetes drug semaglutide orally, rather than as an injection, helped patients with diabetes and heart failure to avoid serious outcomes, including hospitalisation, urgent doctor visits and death, according to an analysis of previous trial data. The study found that, compared to placebo, patients with heart failure taking oral semaglutide had a lower risk of a combined outcome of heart failure hospitalisation, urgent heart failure visit or cardiovascular death over a ten month period. The analysis found no significant benefit for these outcomes in people without heart failure to begin with.

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JAMA Internal Medicine
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Organisation/s: Oregon Health & Science University, USA
Funder: The SOUL trial was funded by Novo Nordisk A/S.
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