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New discovery for treatment of primary liver cancer shows promise in mice
A preclinical study in mice has discovered a drug combination with the potential to treat one of the most fatal and globally widespread cancers, a type of primary liver cancer called hepatocellular carcinoma (HCC).
A preclinical study led by Monash University has discovered a drug combination with the potential to treat one of the most fatal and globally widespread cancers, a type of primary liver cancer called hepatocellular carcinoma (HCC).
The team of researchers from the Monash Institute of Pharmaceutical Sciences (MIPS) found the drug combination reverses the symptoms of nonalcoholic steatohepatitis (NASH) and, subsequently, markedly reduces the onset of NASH-driven HCC, without affecting the liver in mice.
The study, published in Science Advances, used a mouse model that mimics human NASH-driven HCC to implement a combination treatment of an endoplasmic reticulum (ER) stress inhibitor called ‘BGP-15’ with the inflammation blocker, ‘Olamkicept’.
Both of these drugs are already proven to be safe in humans and have progressed to Phase 2 and 3 human clinical trials for other metabolic and/or inflammatory diseases.
The study’s lead author, Professor Mark Febbraio from MIPS, said this is an exciting discovery for a particularly widespread and devastating disease with a low survival rate.
“HCC is increasing at an alarming rate largely due to increased obesity and type 2 diabetes which may lead to NASH, a well known HCC risk factor,” said Professor Febbraio.
The rise in HCC coincides with patients presenting with obesity and symptoms associated with the metabolic syndrome, especially metabolic dysfunction-associated fatty liver disease (MAFLD). Globally, a staggering 25 per cent of the population are estimated to be living with MAFLD, with around 15 per cent of those exhibiting signs of NASH.
“Despite the high prevalence of NASH and the alarming rise in NASH-driven HCC, there are currently no FDA approved treatments that halt disease progression.
“Given that ER stress and inflammation are hallmarks of NASH-driven HCC, and that BGP-15 and Olamkicept have both already proven to be safe, we tested whether these drugs – as monotherapy, or in combination – would prevent NASH and/or NASH driven HCC in mice.
“Consistent with our hypothesis, the study shows that while monotherapy with either of the two drugs modestly slowed progression, when combined they have shown to be a realistic therapeutic strategy for treating human NASH and progression to HCC, diseases that are rapidly growing with a clinical unmet need.”
Professor Febbraio said that given the significance of the discovery, combined with the urgent need for new safe and effective treatments for NASH and NASH-driven HCC, the team ultimately hope their findings will progress toward clinical trials.
“We have to stress that this study was performed in mice, not humans. However, as both drugs have been shown to be safe in several human clinical trials, the logical next step is testing the BGP-15/Olamkicept combination in clinical trials for patients with NASH and or HCC.”
The study was conducted in collaboration with The Garvan Institute of Medical Research; The Salk Institute of Biological Studies based in California; the Faculty of Veterinary Science, University of Sydney; the Baker Heart and Diabetes Institute; the Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia; Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University; Department of Biochemistry, Christian-Albrechts-Universität zu Kiel, based in Germany and the Department of Pharmacology, University of California San Diego, La Jolla, based in California.
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Guilt rather than shame drives us to do the right thing for others
Australia; International
University of Toulouse Capitole, France
Nature Human Behaviour
Stigma silences those with hearing loss
Australia; QLD; SA
Flinders University,The University of Queensland
International Journal of Audiology
Strict rules for short term rentals and Airbnbs no solution to our housing crisis
Australia; SA
University of South Australia
ENTER e-Tourism Conference
Five things you should know about cannabis and psychosis
International
University of Ottawa, Canada
Canadian Medical Association Journal
Couples who meet online less happy in love
Australia; International; ACT
The Australian National University
Telematics and Informatics
Briefing
BACKGROUND BRIEFING: Crunch time for Health Star Ratings as voluntary phase nears end
Australia; NSW
Australian Science Media Centre,George Institute for Global Health,The University of New South Wales,Dietitians Australia,University of Wollongong
Blowing into a conch might help those with sleep apnoea
International
Eternal Heart Care Centre and Research Institute, Jaipur, Rajasthan, IndiaEternal Heart Care Centre and Research Institute, Jaipur, Rajasthan, India
ERJ Open Research
Dancing dwarf galaxies predict our Milky Way's future
Australia; QLD; ACT
The University of Queensland,The Australian National University
Monthly Notices of the Royal Astronomical Society.
Contemplate your ‘inner space’ this National Science Week 9-16 August
Australia; ACT
Food Safety Information Council
AI may be good at parroting medical answers, but it's not so great at reasoning them out
International
Stanford University, USA
JAMA Network Open
Autism symptoms may be milder in young girls, leading to underdiagnosis
International
University of Minnesota, USA
JAMA Network Open
Australian fishery bycatch varies widely between industrial vessels
Australia; QLD; TAS
CSIRO,The University of Queensland,University of Tasmania
Nature Sustainability
Maybe money CAN buy you happiness, but for good health, education is key
International
Loma Linda University, USA
Nature Human Behaviour
When retired robots become part of the family
International
University of Guelph, Canada
Frontiers in Robotics and AI
What do NZ docs think of AI scribes?
New Zealand
University of Otago
Journal of Primary Health Care
New process turns PFAS pollutant into fluoride
Australia; SA
The University of Adelaide
Small
Most donor-conceived Kiwis are told where they come from
New Zealand
University of Auckland,AUT University,University of Otago,University of Canterbury,Fertility Associates, NZ; Te Whatu Ora; American University, USA
Fertility and Sterility
A Mediterranean-style diet may help stave off dementia, Alzheimer's
International
Rush University Medical Center, USA
JAMA Network Open
Let's eat nana: Ancient Spanish cave remains reveal evidence of cannibalism
International
Catalan Institute of Human Paleoecology and Social Evolution (IPHES), Spain
Scientific Reports
One of Patagonia's most stable glaciers is now retreating faster than previously thought
International
Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany
Communications Earth & Environment
Do we have enough critical minerals to transition to a low-carbon world?
International
Beijing Institute of Technology, China
Nature Climate Change
Expert Reaction
EXPERT REACTION: Imagining a space mission to a black hole
International
Fudan University, China
iScience
Co-designed school-based recommendations to support First Nations youth living with type 2 diabetes
Australia; VIC; QLD; WA; NT; ACT
Menzies School of Health Research,Charles Darwin University,The Australian National University,Telethon Kids Institute,Murdoch Children's Research Institute (MCRI)
Australian and New Zealand Journal of Public Health
Hop back in time to find a new Aussie relative of New Guinea’s forest-wallaby
Australia; Pacific; SA
Flinders University
Alcheringa: An Australasian Journal of Palaeontology.
Invisible material could revolutionise smart tech
Australia; VIC
La Trobe University,Deakin University,Monash University,CSIRO,Swinburne University of Technology
ACS Applied Materials and Interfaces
Shining a light on a new principle in photochemistry
Australia; International; QLD
Queensland University of Technology (QUT)
JACS
How to make the best choices: start exploring like a child
Australia; NSW
The University of New South Wales
Neighbourhoods may hold the key to slowing cognitive decline
Australia; NSW; VIC
The University of New South Wales,Australian Catholic University
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Beyond the band-aid: a career opportunity as a school nurse
Australia; WA
Edith Cowan University
Journal of School Nursing
Microearthquakes in New Zealand's Southern Alps more common during spring and summer
Australia; New Zealand; International; ACT
The Australian National University,Victoria University of Wellington
Geochemistry, Geophysics, Geosystems
Why forgiving yourself is harder than it sounds
Australia; International; SA
Flinders University
Self and Identity
Your lifestyle could be affecting your brain’s ‘brake system’ and putting you at a higher risk of dementia
Australia; QLD
University of the Sunshine Coast
Cerebral Cortex
Hot chips may increase your diabetes risk, but boiled, mashed or baked spuds do not
International
Harvard T.H. Chan School of Public Health, USA
The BMJ
New underwater evidence may support controversial idea that a comet exploded and changed the Earth 12,800 years ago
Australia; International; SA
Flinders University,University of South Carolina, USA
PLOS One
Cockatoo dance moves probably put yours to shame
Australia; NSW
Charles Sturt University
PLOS One
440 deaths in LA were likely an indirect result of the January wildfires
Pacific; International
Paper 1: University of Helsinki, Finland. Paper 2: New York University, USA. Paper 3: University of Hawaii, USA
JAMA, JAMA Network Open
Trans and nonbinary people experience worse mental health than the rest of the population
International
University of Glasgow, UK
JAMA Psychiatry
Changes to El Niño occurrence causing widespread tropical insect and spider declines
Australia; International; QLD
Griffith University,Hong Kong University
Nature
Does lithium deficiency play a role in Alzheimer's disease?
International
Harvard Medical School, USA
Nature
Archaeologists find oldest evidence of humans on ‘Hobbit’s’ island neighbour – who they were remains a mystery
Australia; International; NSW; QLD
Griffith University,University of Wollongong,Southern Cross University,The University of New England
Nature
Air purifiers could help heart health among those exposed to traffic pollution
International
University of Connecticut, USA
Journal of the American College of Cardiology (JACC)
New cooling system patent promises significant boost in solar panel efficiency
International
University of Sharjah
Google Patents
Planting shady trees near cocoa crops could help make your chocolate carbon neutral
International; QLD
The University of Queensland,ETH Zurich, Switzerland
Nature Sustainability
No evidence between diabetes in pregnancy and educational outcomes
Australia; VIC
The University of Melbourne,Deakin University
Diabetes Care
Liquid fat treatment offers hope for rare childhood disease
Australia; NSW; VIC; QLD
The University of Queensland,Griffith University,CSIRO,The University of Melbourne,Garvan Institute of Medical Research,The University of New South Wales,QIMR Berghofer
eBiomedicine
Experts urge shift in heatwave strategy to save lives
Australia; International; NSW
The University of Sydney
Nature
Treatment for sleep apnoea is good for the heart in some patients but bad for others
Australia; NSW; SA
Flinders University,The University of Adelaide,George Institute for Global Health,The University of New South Wales,Harvard Medical School, USA
European Heart Journal
Expert Reaction
Songbirds need their sleep to sing
New Zealand
University of Auckland,University of Waikato
Proceedings of the Royal Society B: Biological Sciences
Sustained benefits from mind and body treatment for back pain
Australia; NSW; WA
Macquarie University,Curtin University
Lancet Rheumatology
‘Solastalgia’ might help explain the negative effects of climate change on mental health
Australia; International
University of St Gallen, Switzerland
BMJ Mental Health
Expert Reaction
Childhood verbal abuse shows similar impact on adult mental health as physical abuse
International
Liverpool John Moores University, UK
BMJ Open
Revealed: new vaccine target to block malaria transmission
Australia; International; VIC
WEHI,Monash University,The University of Melbourne
Science
Boosting AI to read chest X-rays smarter and more accurately
Australia; QLD
CSIRO
arXiv
Young chimps learn to communicate from their mums
International
University of Zurich, Switzerland
PLOS Biology
Obesity runs in the family, but it might be more likely thanks to mum
International
University College London, UK
PLOS Genetics
A robotic folding sheet could crawl its way into exploration and healthcare
International
Korea Advanced Institute of Science and Technology, Korea
Nature Communications
Great Barrier Reef more volatile with sharp declines in coral cover
Australia; International; QLD
Australian Institute of Marine Science (AIMS)
New treatment on trial for panic disorder
Australia; SA
South Australian Health and Medical Research Institute (SAHMRI)
Policies to restrict opioid prescriptions linked to a drop in opioid‐related ED visits
Australia; NSW; VIC
Monash University,The University of New South Wales
Medical Journal of Australia
How Aussie skinks outsmart lethal snake venom
Australia; International; NSW; QLD; SA
The University of Queensland,The University of Sydney,South Australian Museum,The University of Adelaide,Flinders University,James Cook University
International Journal of Molecular Sciences
Adults with disability are experiencing extreme loneliness at greater rates than the rest of the population
International
Brown University, USA
Annals of Internal Medicine
A low-calorie diet likely won't directly help hip osteoarthritis pain but could still have health benefits
Australia; NSW; VIC
The University of Sydney,The University of Melbourne,Monash University,The University of Newcastle
Annals of Internal Medicine
Ecolabels on restaurant menus could help reduce carbon emissions
International
Stanford University School of Medicine, USA
JAMA Network Open
Reported Tamiflu side effect on mental health in kids may just be down to the flu virus
International
Vanderbilt University Medical Center, USA
JAMA Neurology
Not all big dinosaurs had strong chomps
International
University of Bristol, UK
Current Biology
Lowering the bowel cancer screening age to 45 shows benefits in the US
International
American Cancer Society, University of California, UTHealth Houston School of Public Health
JAMA
Researchers identify culprit behind sea star wasting disease
International
The University of British Columbia, Canada
Nature Ecology & Evolution
Healthy but ultra-processed diets may undermine weight loss efforts
International
University College London (UCL), UK
Nature Medicine
Hidden bowel cancer risk in common growths
Australia; SA
Flinders University
Clinical Gastroenterology and Hepatology
What determines who becomes and stays friends? It might be all in your head
International
University of California, USA
Nature Human Behaviour
Which scientists are using AI-generated language in their research papers?
International
Stanford University, USA
Nature Human Behaviour
Developing a method to optimise delivery of mRNA to cells
Australia; VIC
Monash University
Nature Nanotechnology
Gold to green: direct seeding transforms sand mine rehabilitation in SEQ
Australia; QLD
Griffith University
Ecological Engineering
Findings show NT’s vital water source is drying – and it can be seen from space
Australia; QLD; NT
Griffith University
Ecological Informatics
From waste to energy – weeds as a source of biofuel
Australia; QLD
The University of Queensland
Sustainable Energy Technologies and Assessments
Engineered stone workers have high rates of asthma, even if they don't have silicosis
Australia; VIC
Monash University
Occupational and Environmental Medicine
Expert Reaction
EXPERT REACTION: Heart disease hospitalisations jump after a tropical cyclone
Australia; New Zealand; International; VIC
Monash University,University of Otago
Science Advances
Kids are spending about an hour per school day on their phones
International
The University of North Carolina at Chapel Hill, USA
JAMA Network Open
Hearing loss linked to lower prospects of employment and educational attainment
International
University of Florida, USA
Frontiers in Otology
Trigger warnings fall flat, but safe spaces build trust in the classroom
Australia; International; SA
Flinders University
Journal of Experimental Psychology Applied
‘Life-changing’ genetic link offers hope for millions who stutter
Australia; International; WA
Curtin University
Nature Genetics
Climate interventions to save our oceans need stronger governance
Australia; International; VIC; QLD; TAS
The University of Melbourne,James Cook University,University of Tasmania,The University of Queensland,Australian Institute of Marine Science (AIMS),The University of Exeter, UK
Science
Traces of deadly synthetic opioids found at needle and syringe disposal sites in SA
Australia; SA
University of South Australia
Drug and Alcohol Review
AI supports quicker responses to emerging public health risks
Australia; QLD
The University of Queensland
JAMA Network Open.
Twinkle, twinkle leopard seal: songs below the ice flow like nursery rhymes
Australia; International; NSW
The University of New South Wales
Scientific Reports
Love a potato? Thank a tomato
International
Chinese Academy of Agricultural Sciences, China
Cell
Quad bike deaths have reduced since Aussie safety standards changed in 2019
Australia; NSW
The University of Sydney
Australian and New Zealand Journal of Public Health
Megaflash stretching 829km sets new world record for the longest lightning strike
International
World Meteorological Organization (WMO)
More expectant mums in Australia are accessing antenatal care
Australia
Australian Institute of Health and Welfare (AIHW)
Ancient Thai teeth show we've been getting a buzz from betel nuts for at least 4,000 years
Australia; International; VIC
Chiang Mai University, Thailand, California Academy of Sciences, USA, Unearthed Heritage Australia
Frontiers in Environmental Archaeology
Briefing
testtestestsawd
New Zealand
Agilent Technologies Australia,Ambulance Victoria
no
National drug trial shows early promise for treatment of rare blood cancer
Australia; International; VIC; SA
South Australian Health and Medical Research Institute (SAHMRI),University of South Australia,The University of Melbourne
Blood
Muscle over mass could be the key to recruit success
Australia; NSW; VIC; QLD; SA; WA
Edith Cowan University,University of Technology Sydney (UTS),Flinders University,Queensland University of Technology (QUT),Southern Cross University,Deakin University
Functional Morphology and Kinseology
Actual distance travelled by migrating whales drastically underestimated
Australia; International; QLD
Griffith University
Ecology
From cancer therapeutics to critical minerals recovery - Building tech to secure the world’s critical metals
Australia; International; NSW; SA
ARC Centre of Excellence for Enabling Eco-Efficient Beneficiation of Minerals,Australian Research Council (ARC)
Advanced Functional Materials Journal
Expert Reaction
EXPERT REACTION: An mRNA vaccine for HIV could be effective and affordable
International
Fred Hutchinson Cancer Center, USA
Science Translational Medicine
Students consistently exposed to hotter temperatures are falling behind in school
Australia; NSW; VIC
RMIT University,The University of New South Wales
PLOS Climate
Expert Reaction
EXPERT REACTION: We may be breathing in tens of thousands of teeny tiny microplastics every day
International
University of Toulouse, France
PLOS One
Instagram images could influence public opinion on certain major events
International
Istanbul Medipol University, Türkiye; University of Calgary, Canada; University of Southern Denmark, Denmark
PLOS One
Gender-affirming treatments may be altering the hearts of trans people to match their target gender
International
Sorbonne Université, France
JAMA Network Open
New method to detect gastric cancer without an invasive endoscopy
International
Beckman Research Institute of City of Hope, US
JAMA Surgery
Pain reprocessing therapy could help those with mild chronic back pain
International
University of Colorado, USA
JAMA Psychiatry
Are magic mushrooms really that great for treating depression?
International
University of Gothenburg, Gothenburg, Sweden
JAMA Network Open
COVID-19 and the flu could increase the risk of dormant cancer spreading
International
University of Colorado, USA
Nature
What lurks in the deepest, darkest depths of the ocean where there is no sunlight?
International
Chinese Academy of Sciences, China
Nature
All sustainable roads may lead to Roman concrete
International
Universidad del Norte, Columbia
iScience
Life 'flourishing' many kilometres deep in the Pacific ocean
New Zealand; Pacific; International
Victoria University of Wellington,National Institute of Water and Atmospheric Research (NIWA),Institute of Deep-sea Science and Engineering, China
Nature
Neighbourhood watch: why closely related tropical animals live together
Australia; International; NSW
Macquarie University,The University of New South Wales,University of Nebraska, USA
Proceedings of the Royal Society B
Expert Reaction
EXPERT REACTION: Australian-made rocket launches and crashes in Queensland
Australia; NSW; VIC; QLD
Australian Science Media Centre
Expert Reaction
EXPERT REACTION: Magnitude 8.8 quake east of Russia
New Zealand; Pacific; International
Treating hypertension with single pill combinations saves lives and money
Australia; International; NSW
George Institute for Global Health,The University of New South Wales
Journal of Hypertension
How far dingoes roam depends on whether they are top dog
Australia; NSW
The University of New South Wales,Macquarie University,The University of Sydney,Taronga Conservation Society Australia
Royal Society Open Science
Exercise rehabilitation could lessen severity and frequency of heart issues
Australia; International
University of Liverpool, UK
British Journal of Sports Medicine
Higher ultra-processed food intake could be linked to lung cancer risk
International
Chongqing University Cancer Hospital, China
Thorax
Hate speech and psychiatric disorder communities share similar speech patterns on Reddit
International
Texas A&M University, USA
PLOS Digital Health
The DNA analysis device that can be made on a 3D printer
Australia; QLD
Australian Institute for Bioengineering and Nanotechnology (AIBN)
bioRXiv
When is it too hot to use a fan?
Australia; NSW; VIC; SA
The University of Sydney,Monash University,The University of Adelaide,Montreal Heart Institute, Canada
JAMA Network Open
Adolescents with mental health disorders at higher risk of developing gaming disorders
International
University of California, USA
JAMA Network Open
How digital twins can accelerate the global transition from fossil fuels to clean energy
International
University of Sharjah, UAE
Energy Nexus
Risk of deadly diarrhoeal diseases in children set to worsen as climate changes
Australia; Pacific; SA; WA
Flinders University,The Kids Research Institute Australia,The University of Western Australia
Environmental Research
New remote-sensing system maps in fine detail Antarctica’s unique vegetation
Australia; NSW; QLD
Queensland University of Technology (QUT),University of Wollongong
Scientific Reports
How much time did our ancestors spend climbing trees?
International
Max Planck Institute for Evolutionary Anthropology, Germany
Frontiers in Ecology and Evolution
A single bout of exercise gives results
Australia; WA
Edith Cowan University
Breast Cancer Research and Treatment
Chemical ‘leakage’ adds urgency to calls for a robust world plastics treaty
Australia; International; SA
Flinders University
UN INC policy brief
Class divided: How Aussie highschoolers are separated on ability
Australia; NSW; QLD; WA
Edith Cowan University,The University of Newcastle,The University of Western Australia,Queensland University of Technology (QUT)
Educational Studies
Citizen science drives countless new discoveries
Australia; International; NSW; VIC
The University of New South Wales,Monash University
BioScience
After 250 years, Mount Vesuvius artwork erupts into life
Australia; VIC
The University of Melbourne
Urban food production ticks all boxes for more sustainable living – here’s why
Australia; SA
Flinders University,The University of Adelaide
Urban Forestry & Urban Greening
Liver cancers are set to double in the next 25 years, but we can change that
International
The Chinese University of Hong Kong, China, Baylor College of Medicine, USA, Public Assistance-Hospitals of Paris, France, Fudan University, China, Kindai University, Japan
The Lancet
Stronger, cheaper titanium a ‘leap forward’ for industry
Australia; International; VIC
RMIT University
Nature Communications
How can we support brain health as we age?
International
Wake Forest University School of Medicine, USA
JAMA
Controlling gut bugs? There's an app for that
International
Tianjin University, China, Northwest Agriculture and Forestry University, China
Nature Microbiology
Spotlight on technology to protect older Australians from respiratory infections
Australia; SA
Flinders University,South Australian Health and Medical Research Institute (SAHMRI)
JAMA Internal Medicine
Warmer with a chance of ice: Hailstorms could hit Australian cities harder
Australia; NSW
The University of New South Wales
Geophysical Research Letters
Vaping may have slowed Australia's progress in reducing teen smoking
Australia; NSW
The University of Sydney
Medical Journal of Australia
Tropical fishes on the move survive better with temperate neighbours
Australia; NSW; SA
The University of Adelaide
Journal of Animal Ecology
‘Feast and fast’ migration sees whales lose 36% body fat
Australia; International; QLD
Griffith University
Marine Mammal Science
Australian-developed AI to revolutionise early disease detection
Australia; International; WA
Edith Cowan University
International Conference on Digital Image Computing, Techniques and Applications
Trial to investigate medicinal cannabis for debilitating condition
Australia; NSW
Western Sydney University
Genetic weak spot in hard-to-treat cancers revealed
Australia; VIC
WEHI
EMBO Reports
Total IVF births soar to more than 13 million
Australia; NSW
The University of New South Wales
Fertility and Sterility
Exploring symptom prevalence across the menopause transition
Australia; VIC
Monash University
The Lancet Diabetes and Endocrinology
Revealing the Hippo pathway’s secrets in hope of new cancer treatments
Australia; NSW; VIC; QLD; SA
Peter MacCallum Cancer Centre,Monash University,The University of Melbourne,The University of Queensland,The University of Sydney,The University of Adelaide
Science Advances
New discovery could lead to more effective cancer treatment
Australia; NSW; ACT
The Australian National University,Macquarie University
Science Advances
COVID-19 vaccinations likely averted 2.5 million deaths between 2020 and 2024
International
Stanford University School of Medicine, USA
JAMA Health Forum
Scuba diving industry benefits locals and marine life
Australia; International; QLD
James Cook University,University of British Columbia, Canada
Cell Reports Sustainability
Shifting foundations of the Antarctic food web
Australia; International; TAS
Australian Antarctic Program Partnership (AAPP),Institute for Marine and Antarctic Studies (IMAS),University of Tasmania,Danish Meteorological Institute, Denmark
Nature Climate Change
Intense grief linked to a higher risk of death for a decade
International
Research Unit for General Practice, Denmark
Frontiers in Public Health
Crown-of-thorns control boosts coral growth in a warming world
Australia; QLD
The University of Queensland,CSIRO
Journal of Environmental Management
Pre-existing immunity to H1N1 flu might help protect against deadly H5N1 bird flu, at least in ferrets
International
Pennsylvania State University, USA
Science Translational Medicine
Strict regulations for street stalls a drain on vibrancy
Australia; VIC; QLD
The University of Queensland,The University of Melbourne
Urban Planning
Expert Reaction
EXPERT REACTION: Unprecedented ocean heatwaves may signal climate tipping point
Australia; International; NSW; TAS
Eastern Institute of Technology, China
Science
Kākāpō parasites are going extinct
Australia; New Zealand; SA
Manaaki Whenua - Landcare Research,The University of Adelaide,University of Auckland
Current Biology
Weed might weaken cancer immunotherapy, cannabis doc says
Australia; New Zealand
Australani Health
NZMJ
Incentivising business investment in R&D
Australia
Australian Academy of Science
Published Next-Gen Blood Test Predicts Diabetic Kidney Disease Years Before Symptoms
Australia
Proteomics International Laboratories Ltd
Journal of Applied Laboratory Medicine
Expert Reaction
EXPERT REACTION: International Court of Justice says states must act on climate change
Australia; International; NSW; VIC; SA; ACT
Australian Science Media Centre
Grassland changes put endangered parrot at greater risk
Australia; SA
The University of Adelaide
PLOS One
From check-in to baby boom: seahorse 'hotels' boost Sydney’s underwater life
Australia; NSW
The University of New South Wales
And I would walk 7,000 steps: Daily 7k step count could protect you from a range of health issues
Australia; International; NSW; VIC; SA
The University of Sydney,Baker Heart and Diabetes Institute,The University of Adelaide,The University of New South Wales
The Lancet Public Health
Ivermectin may help control malaria
International
Universidad de Navarra, Spain, Barcelona Institute for Global Health, Spain
New England Journal of Medicine
Dinosaur tracks show first evidence of multispecies herding
Australia; International; NSW
University of Reading, UK, The University of New England, Macquarie University
PLOS One
Teens who smoke or vape may have higher rates of depression and anxiety
International
West Virginia University, USA
PLOS Mental Health
How are Pacific Islander communities adapting to climate change?
Australia; Pacific; VIC; QLD
The University of Melbourne,CSIRO,The University of Queensland
PLOS Climate
Deep-sea DNA study reveals global connectivity of marine life
Australia; New Zealand; VIC
Museums Victoria,National Institute of Water and Atmospheric Research (NIWA)
Nature
Moisturising your baby daily could lower their chances of developing eczema
International
Oregon Health & Science University, USA
JAMA Dermatology
A 247-million year old Triassic reptile with a crest of not-quite feathers and not-quite skin
International
Staatliches Museum für Naturkunde Stuttgart, Germany
Nature
Could you swap your mouse and keyboard for a smart bracelet?
International
Reality Labs at Meta, USA
Nature
AI could help us decipher fragmented ancient texts
International
Google DeepMind, UK
Nature
The right fungi in our wheat could make our bread more nutritious
Australia; SA
The University of Adelaide
Plants, People, Planet
Australian data confirm link between mRNA COVID-19 vaccination and menstrual cycle changes
Australia; VIC
Murdoch Children's Research Institute (MCRI),The University of Melbourne
Vaccine
True colours: how red, green and yellow concrete can improve Sydney marine life
Australia; NSW
Macquarie University
Journal of Applied Ecology
Interference to astronomy the unintended consequence of faster internet
Australia; WA
Curtin University,International Centre for Radio Astronomy Research (ICRAR)
Astronomy and Astrophysics
Working up a sweat - understanding how sweat forms, spreads, and evaporates on our skin
International
Arizona State University, USA
Journal of the Royal Society Interface
Battle of the diabetes drugs: GLP-1 RAs vs metformin for dementia
International
Zhengzhou University, China
BMJ Open Diabetes Research & Care
Into the great genome: new tracker for Australia’s genomic biodiversity
Australia
CSIRO
Psychedelics and cannabis offer treatment hope for people with eating disorders
Australia; NSW
The University of Sydney
JAMA Open Network
Leading the way comes at a cost for feathered friends
Australia; ACT
The Australian National University
Current Biology
If you feel like the COVID-19 pandemic aged you, you might be right
International
National Institute for Health Research, UK
Nature Communications
More accurate measures required to help diagnose sepsis in children
Australia; VIC
Murdoch Children's Research Institute (MCRI)
The Lancet Regional Health - Western Pacific
Do some cultures sound angrier than others?
International
University of Geneva, Switzerland
Frontiers in Communication
STIs during pregnancy linked to adverse birth complications
Australia; SA; WA
Curtin University,The University of Adelaide,Edith Cowan University
The Lancet Regional Health – Western Pacific
New stingray species found at Fiji fish market
Australia; Pacific
The University of the South Pacific,CSIRO
Journal of Fish Biology
‘Defying gravity’: Online physio program brings fall prevention into the home
Australia; NSW; VIC
The University of Sydney,NSW Government,Neuroscience Research Australia (NeuRA)
Medical Journal of Australia
In foster and kinship care, who cares about the adult carers?
Australia; SA
Flinders University,The University of Adelaide,University of South Australia
The British Journal of Social Work
Ensuring a good death for those in aged care
Australia; SA
Flinders University
BMC Nursing
On stopping weight loss drugs, many patients find they regain weight
International
Peking University People's Hospital, China
BMC Medicine
Getting all your exercise in on the weekend can still protect your heart
International
Harvard T.H. Chan School of Public Health, USA
Annals of Internal Medicine
First treatments to prevent life-threatening virus infection identified
Australia; VIC; QLD
WEHI,The Peter Doherty Institute for Infection and Immunity,The University of Melbourne,Mater Research,The University of Queensland,Queensland Brain Institute,Centenary Institute
Cell
Stringent environmental regulations may undermine climate goals and renewable energy production
International
University of Sharjah, United Arab Emirates
Energy Policy
Are steroids sold in Australia what they claim to be?
Australia; VIC; QLD
The University of Queensland,Monash University,Griffith University
Drug and Alcohol Review
Gene therapy can outperform a cochlear implant for children with congenital deafness
International
Fudan University, China
JAMA Neurology
Expert Reaction
EXPERT REACTION: 4-day workweek makes workers happier and more confident at their jobs
Australia; New Zealand; International
Boston College, USA
Nature Human Behaviour
Drownings in Australia have fallen by a quarter over 20 years
Australia; NSW; QLD
James Cook University,The University of New South Wales,Royal Life Saving Society
Australian and New Zealand Journal of Public Health
How traditional bush foods are transforming health and school attendance
Australia; WA
Murdoch University
Children who get their first smartphone before age 13 face higher mental health risks
International
Sapien Labs, USA
Journal of Human Development and Capabilities
New-age and old school shark bite prevention strategies put to the test on Gold Coast beaches
Australia; NSW; QLD; SA; WA; TAS
Flinders University,The University of Queensland,James Cook University,Southern Cross University,NSW Government,Government of Western Australia,Bond University,Queensland Government,University of Tasmania
People and Nature
Expert Reaction
EXPERT REACTION: Should SA's toxic algal bloom be declared a national disaster?
Australia; NSW; SA
Australian Science Media Centre
Big changes to Australia’s largest animals over 100,000 years reveal mammals are most vulnerable
Australia; NSW; QLD; SA
Flinders University,ARC Centre of Excellence for Australian Biodiversity and Heritage (CABAH),University of Technology Sydney (UTS),Australian Museum,The University of Queensland,The University of Sydney
Quaternary Australasia
Knowing better, doing worse: The science behind self-sabotaging behaviour
Australia; NSW
The University of New South Wales,Neuroscience Research Australia (NeuRA)
Nature Communications Psychology
Scientists uncover hidden bone structures in the skin of Australian monitor lizards and it could unlock the secrets to their evolutionary success
Australia; VIC
Museums Victoria
Zoological Journal of the Linnean Society
Co-infections in young bats could underpin coronavirus emergence
Australia; NSW; QLD
The University of Sydney,Griffith University,The Westmead Institute for Medical Research
Nature Communications
Low vitamin D may increase your risk of being hospitalised with COVID-19
Australia; International; SA
University of South Australia,King’s College London, UK
PLOS One
How do the new diabetes drugs stack up against the old for cancer patients?
International
University of Florida, USA
JAMA Network Open
Hungry bugs and disappearing bioplastics hold key to ending plastic waste crisis
Australia; International; WA
Murdoch University,CSIRO
‘AI is not intelligent at all’: Why our dignity is at risk
Australia; NT
Charles Darwin University,The University of Melbourne
Australian Journal of Human Rights
Recycled tyre tech boosts railway resilience and cuts waste
Australia; NSW
University of Technology Sydney (UTS)
Canadian Geotechnical Journal
New COVID-19 vaccine candidate shows strong protection against multiple variants in mouse study
Australia; NSW
Centenary Institute,The University of Sydney
npj Vaccines
Decades of surveys show whale migration shift
Australia
The University of Queensland
Scientific Reports
Android's quake detection provides early warning for a third of users
International
Google LLC, USA; University of California, Berkeley, USA
Science
Expert Reaction
EXPERT REACTION: Is gene editing the next frontier of conservation?
International
University of East Anglia, UK; Colossal Biosciences, USA
Nature Reviews Biodiversity
Could we use global smartphone networks to predict earthquakes?
International
Google, USA
Science
Cancer patients who received a COVID-19 booster vaccine were less likely to be hospitalised with the virus
International
Kaiser Permanente Northern California, USA
JAMA Oncology
Can we predict a bird flu outbreak?
International
Heidelberg University, Germany
Scientific Reports
Dogs might have TV preferences based on their personality
International
Auburn University, USA
Scientific Reports
Neanderthals at two nearby caves butchered the same prey in different ways
International
The Hebrew University of Jerusalem, Israel
Frontiers in Environmental Archaeology
New dual-drug strategy shows promise against aggressive leukaemia
Australia; NSW; VIC
Peter MacCallum Cancer Centre,Monash University,The University of New South Wales
Cancer Discovery
‘Ultimate dinner party guests’: Dispersed communities attending feast in ancient Iran gifted boars sourced from distant lands
Australia; QLD; SA; ACT
The Australian National University,Griffith University,The University of Adelaide,Southern Cross University
Nature Communications Earth and Environment
Australia’s future science and technology leaders land in Melbourne to kickstart their future
Australia; VIC
National Youth Science Forum
Spinal cord stimulators: ineffective treatment found to be costly and risky
Australia; NSW; VIC
The University of Sydney,Monash University,The University of New South Wales
Medical Journal of Australia
Briefing
Expert Reaction
EXPERT REACTION and MEDIA BRIEFING: First babies born in the UK through mitochondrial donation
Australia; International; VIC
Monash University,Newcastle Fertility Centre, UK, Newcastle University, UK
New England Journal of Medicine
Reanimating a heart after death for organ transplant
International
Duke University Medical Center, USA, Vanderbilt University Medical Center, USA
New England Journal of Medicine
Reducing food insecurity could significantly reduce anxiety and depression
International
Newcastle University, UK
PLOS Mental Health
Trump's climate rollbacks could be causing a public health emergency
International
Vanderbilt University, USA
PLOS Climate
We might be more likely to believe men's tears are genuine
International
University of Lodz, Poland
PLOS One
Emotion to our ears: Hearing aids that amplify all sound levels might restore the ability to hear emotion in voices
International
Linköping University, Sweden
PLOS One
Walking just 14 steps a minute faster could help older people improve their endurance
International
University of Chicago, USA
PLOS One
Whether the super rich stash their cash offshore is influenced by politics at home
Australia; New Zealand; International
Dartmouth College, USA
PLOS One
People who don't get the flu shot are being protected by those who do
International
University of Pittsburgh, USA
JAMA Network Open
Children from a town contaminated by radioactive waste have faced a higher cancer risk throughout life
International
Harvard T. H. Chan School of Public Health, USA
JAMA Network Open
LGBT adults are more likely to report having a disability
International
RAND, USA
JAMA Network Open
Where did all the antimatter go? This mismatch in how subatomic particles behave could hold a clue
Australia; International; VIC
Monash University,LHCb Collaboration, INFN Sezione di Genova, Italy
Nature
Telescope images show planets beginning to form around baby star
International
Leiden University, The Netherlands
Nature
Ancient 'dolphin' fins could help shush ships for their modern-day counterparts
International
Lund University, Sweden
Nature
Lunar soil could support life on the Moon
International
Nanjing University, China
Joule
Restored wetlands reap benefits for climate, drought-resilience after just one year
Australia; VIC
RMIT University,Deakin University
Journal of Environmental Management
Wastewater contaminants boost green hydrogen production
Australia; VIC
RMIT University
ACS Electrochemistry
Fitness tracker data shows running too fast can be deadly for bearded dragons
Australia; VIC
The University of Melbourne
Journal of Animal Ecology
Telehealth works but rules need changing
Australia; SA
Flinders University,The University of Adelaide
Health & Social Care in the Community
From orchard to fridge: Helping mangoes stay sweet for longer
Australia; WA
Edith Cowan University
Plant Growth Regulation
Aussie sponge carrying dolphins' tool use might come at the cost of echolocation
Australia; WA
Curtin University,Georgetown University, USA
Royal Society Open Science
Finding the voice of a critically endangered Australian dolphin
Australia; VIC; WA
Curtin University,Marine Mammal Foundation, Australia
Royal Society Open Science
Decoding eye contact
Australia; NSW; SA
Flinders University,Macquarie University
Royal Society Open Science
Some players are spending more on loot boxes than they can afford
Australia; TAS
University of Tasmania
Royal Society Open Science
These mild forms of exercise could help ease your insomnia
International
Beijing University of Chinese Medicine, China
BMJ Evidence-Based Medicine
Before the lump: a simple blood test to detect cancer early
Australia; NSW; VIC
The University of New South Wales
Playing an instrument may keep our brains fit as a fiddle as we age
International
Chinese Academy of Sciences, China
PLOS Biology
Rethinking the role of genetic variant in late-onset Alzheimer’s, Parkinson's and other neurodegenerative diseases
Australia; International; NSW
The Westmead Institute for Medical Research,The University of Sydney
Nature Medicine
New diabetes and weight loss drugs could be reducing the risk of dementia and stroke
International
Chang Gung Memorial Hospital, Taiwan
JAMA Network Open
Depression linked to ‘internal jet lag’
Australia; NSW
The University of Sydney
Journal of Biological Rhythms
AI divide is hindering healthcare progress in the Global South
International
University of Sharjah, UAE
Digital Health
Which supermarket depression treatments work?
International
Liverpool John Moores University, UK
Frontiers in Pharmacology
Expert Reaction
EXPERT REACTION: Landmark Australian Climate Case ruling
Australia; NSW; VIC; QLD; SA
Australian Science Media Centre
Maternity costs are lower in private vs public maternity care
Australia; NSW; VIC; ACT
Monash University,University of Technology Sydney (UTS),The Australian National University
BJOG: An International Journal of Obstetrics & Gynaecology
Expert Reaction
89% of the world's children received key childhood vaccine last year
International
World Health Organization (WHO)
New route into cells could make gene therapies safer
Australia; International
Centenary Institute,The University of Sydney
Cell
Rethinking wildlife tourism: Ruling out ‘orangutan kickboxing’ a good start to limit harmful animal objectification
Australia; QLD
Griffith University
Journal of Agricultural and Environmental Ethics
Children don't fill the void after the death of a spouse
International
University of Siegen, Germany
Aging & Mental Health
Aluminium in childhood vaccines not linked to autoimmune, allergic, or neurodevelopmental disorders
International
Statens Serum Institut, Denmark
Annals of Internal Medicine
Diabetes patients on Ozempic-like drugs more likely to develop gastroesophageal reflux disease
International
Jewish General Hospital, Canada
Annals of Internal Medicine
Vaping more effective at helping socially disadvantaged people quit smoking compared to nicotine gum or lozenges
Australia; NSW; VIC; QLD
National Drug and Alcohol Research Centre (NDARC),The University of Newcastle,Monash University,Deakin University,The University of Queensland,The University of New South Wales,Bond University
Annals of Internal Medicine
New technique can dramatically improve laser linewidth
Australia; NSW
Macquarie University
APL Photonics
Scientists can tell what you'll buy by scanning your friends' brains
International
Shanghai International Studies University, China, Joint Lab of Finance and Business Intelligence, China
JNeurosci
Whether you can enjoy healthy ageing depends on where you live
Australia; International; NSW
The University of Sydney,Trinity College Dublin, Ireland
Nature Medicine
Almost 4 in 10 Australians living with multiple chronic health conditions
Australia
Australian Institute of Health and Welfare (AIHW)
Scientists unlock ancient cellular wisdom of brain stem cells, offering hope for brain cancer and degenerative disease
Australia; QLD
QIMR Berghofer,The University of Queensland,Queensland University of Technology (QUT)
Science Advances
If you think its a jungle out there you might admire an aggressive leader
International
Columbia University, USA
Journal of Personality and Social Psychology: Attitudes and Social Cognition
Tracking muscle damage in racehorses: New test to optimise recovery and performance
Australia; WA
Proteomics International Laboratories Ltd,The University of Western Australia
Veterinary Medicine and Science
Bowel cancer survivors at higher risk of subsequent cancers
Australia; SA
Flinders University
Cancer Medicine
Revealing the hepatitis B risks for First Nations people in the Northern Territory
Australia; VIC; NT
Menzies School of Health Research,Charles Darwin University,The Peter Doherty Institute for Infection and Immunity
BMC Infectious Diseases
Learning music helps young people flourish
Australia; WA
Edith Cowan University
Research Studies in Music Education
Food taxes and subsidies could transform Australians' diets
Australia; NSW
George Institute for Global Health,The University of New South Wales
Nature Food
Long term obesity from childhood could make you age faster
International
Universidad de Chile
JAMA Network Open
'Molecular shield' in the nose could one day treat common hayfever trigger, mouse study suggests
International
Kazakh National Agrarian Research University, Kazakhstan
Frontiers in Immunology
Artificial sweeteners leave bitter aftertaste for the environment
Australia; NSW
University of Technology Sydney (UTS)
Journal of Hazardous Material
We dammed so much water it moved Earth's poles
International
Harvard University, USA
Geophysical Research Letters
Untapped potential of semen for men’s health
Australia; SA
The University of Adelaide
Nature Reviews Urology
Are sports playing the role of religion in modern life?
Australia; ACT
University of Canberra
Using First Nations calendars for solar power forecasting
Australia; NT
Charles Darwin University
IEEE Open Journal of the Computer Society
High-tech dive into 'mighty bite' of ancient lungfish
Australia; International; SA; WA; ACT
Flinders University,Australian Nuclear Science and Technology Organisation (ANSTO),Curtin University
iScience.
Staying physically active cuts risk of early death by 40%
Australia; QLD
The University of Queensland
British Journal of Sports Medicine
Nerve pain drug may increase risk of dementia
International
Case Western Reserve University School of Medicine, USA, Arizona State University, USA
Regional Anesthesia & Pain Medicine
Exposure to a common type of medication could make you age faster
Australia; International; SA
South Australian Health and Medical Research Institute (SAHMRI),University of Washington, USA
JAMA Network Open
Most high-risk mental health calls to 1737 come from women and teens
New Zealand
AUT University,Whakarongorau Aotearoa , New Zealand Telehealth Services,
New Zealand Medical Journal
Steps towards equitable lung cancer care, but barriers remain
New Zealand
University of Otago,University of Waikato,Te Whatu Ora - Health New Zealand,University of Auckland
New Zealand Medical Journal
Māori less likely to receive best available lung cancer treatment
New Zealand
University of Waikato,University of Auckland,Waikato Hospital
New Zealand Medical Journal
Psychedelic therapy for depression needs to be equitable - editorial
New Zealand
University of Canterbury,Elimbias Health
New Zealand Medical Journal
Hot weather causes children to sweat at the same rate as adults, study shows
Australia; NSW; SA; ACT
The University of Sydney,University of Canberra,University of South Australia
British Journal of Sports Medicine
Superbugs in wastewater? Just add rhubarb and turmeric
International
Utah State University, USA
Frontiers in Microbiology
Feral-free zones spark small mammal boom in Australian desert
Australia; NSW; SA
The University of New South Wales,The University of Adelaide
Proceedings of the Royal Society B
Global vaccine stockpiles prevented more than 5.8 million cases
Australia; VIC
Burnet Institute,Monash University,The University of Melbourne
BMJ Global Health
Cancer survivors could be missing out on exercise benefits
Australia; NSW; QLD; SA; WA
Edith Cowan University,The University of Adelaide,The University of Sydney,The University of Queensland
Supportive Care in Cancer
Tracking insect and bug health in a heartbeat from a digital camera
Australia; SA
University of South Australia
Archives of Insect Biochemistry and Physiology
More support needed for police mental health
Australia; New Zealand; NSW
University of Technology Sydney (UTS)
The Journal of Forensic Practice
Health experts’ 8 recommendations for the UN Plastics Treaty
Australia; International; NSW
The University of Sydney
Bulletin of the World Health Organization
Underwater robots inspired by real eels
International
Guiyang University, China
PLOS One
5 cancers may be more common among the less well off
International
Kanagawa Cancer Center Research Institute, Japan
PLOS One
Lonely people may be more likely to have poor physical and mental health
International
Howard University, USA
PLOS One
NZ's oldest burial site risks being swallowed by the sea
New Zealand
National Institute of Water and Atmospheric Research (NIWA),Massey University,Te Rūnanga a Rangitāne o Wairau Trust
MAI Journal
What symptoms might you experience after you stop taking antidepressants?
Australia; International; VIC
Deakin University,Imperial College London, UK
JAMA Psychiatry
The bacteria, viruses and parasites that have plagued humans for over 37,000 years
Australia; International; WA
Curtin University,University of Copenhagen, Denmark
Nature
The Atlantic Ocean is swimming in nanoplastics
International
Helmholtz Centre for Environmental Research - UFZ, Germany
Nature
Whale poo shows rising ocean temperatures linked to more algal bloom toxins entering the food chain
International
NOAA Fisheries, USA
Nature
Dancing to the same tune: Live performances sync brainwaves
International
University College London, UK
iScience
What factors affect the success of weight loss drugs?
International
Peking University People’s Hospital, China
Diabetes, Obesity and Metabolism
Healthy plant-based diet linked to a reduced risk of inflammatory bowel disease
International
Zhejiang University School of Medicine, China.
Molecular Nutrition and Food Research
Long COVID and chronic fatigue may share features in common
International
Stanford University, USA
PNAS
Culturally diverse WA kids face disadvantage from day one at school
Australia; WA
Curtin University
World Journal of Paediatrics
Keeping rabbits, cats and foxes out of this reserve has helped our small animals bounceback
Australia; NSW; SA
The University of New South Wales,The University of Adelaide,Arid Recovery
Proceedings of the Royal Society B
Sid the sloth's Ice Age migration unusually energetic
International
Universidad de la República, Uruguay
Proceedings of the Royal Society B
Coldplay's music has become blander, but Radiohead have kept it interesting
International
Durham University, UK
Royal Society Open Science
Fish mass is 34% higher in Australia's marine protected areas, but only if all fishing is banned
Australia; SA; TAS
University of Tasmania,The University of Adelaide
Proceedings of the Royal Society B
Tree pollen reveals 150,000 years of monsoon history—and a warning for Australia’s northern rainfall
Australia; NSW; QLD; SA
Flinders University,James Cook University,ARC Centre of Excellence for Australian Biodiversity and Heritage (CABAH),University of Wollongong,University of Technology Sydney (UTS)
Quaternary Science Reviews
COVID, flu & other nasties: what to expect this season and beyond
Australia; NSW
The University of New South Wales
We're told to limit processed foods, but do we know what that means?
International
George Washington University, USA
JAMA Network Open
Quantum battery device lasts much longer than previous demonstrations
Australia
RMIT University,CSIRO
PRX Energy
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