Your genes can increase your risk of endometriosis and mental health disorders at the same time

Embargoed until: Publicly released: 2023-01-19 03:00

International

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The link between endometriosis and several mental health disorders including depression and anxiety is genetic, according to international researchers. The team compared genetic information for 8276 women with endometriosis with nearly 200,000 women without the condition. Accounting for a range of external factors, the researchers say endometriosis was associated with increased odds of depression, eating disorders and anxiety. They say they found evidence of a locus, or specific physical location of a gene that is associated with both endometriosis and mental health disorders, suggesting the association between the conditions is genetic.

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Journal/
conference: JAMA Network Open

Research:Paper

Organisation/s: Yale School of Medicine, USA

Funder: This study was supported by grant 101028810 from the Horizon 2020 Marie Sklodowska-Curie Individual Fellowship from the European Commission (Dr Koller), grants R33 DA047527 and R21 DC018098 from the National Institutes of Health (Dr Polimanti), and One Mind (Dr Polimanti).

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