mRNA COVID-19 jab immunity wanes after 3 months

Embargoed until: Publicly released: 2021-12-16 03:00

International

Photo by Mat Napo on Unsplash

COVID-19 immunity after Pfizer and Moderna mRNA vaccines begins to wane around three months after the second dose and accelerates at four months, according to a US study of veterans during a Delta wave. The researchers looked at data from nearly 15,000 male veterans over 65 to see how well the vaccines were protecting them from any infection before and during the spread of Delta. While the vaccines were 94.5 per cent effective at preventing infection before Delta, decreasing to 87.9per cent after three months, they were 62 per cent effective during Delta, decreasing to 57.8 per cent after three months. The researchers say the fact that the study group was entirely older men could impact the results of this study.

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conference: JAMA Network Open

Research:Paper

Organisation/s: White River Junction Veterans Affairs Medical Center, USA

Funder: This project was funded by the US Department of Veterans Affairs Office of Rural Health. Dr Young-Xu and Mr Smith reported receiving funding from Pfizer.Ms Zwain reported receiving grants from the US Food and Drug Administration through an interagency agreement with the Veterans Health Administration and from the US Department of Veterans Affairs Office of Rural Health. Ms Zwain also reported receiving funding from Pfizer to her employer for other research projects outside the submitted work. Mr Powell reported receiving grants from the US Department of Veterans Affairs Office of Rural Health, the US Food and Drug Administration, and Pfizer. No other disclosures were reported

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