Twice-a-year jab could help lower your blood pressure

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Image by tomwieden from Pixabay
Image by tomwieden from Pixabay

Keep forgetting to take your blood pressure medication? A new clinical trial may have the answer after it showed that a single injection of a drug called zilebesiran can significantly lower blood pressure for up to 6 months. The drug works through RNA interference - which is when small pieces of RNA stop proteins from being made by binding to the RNA that codes for those proteins. The study found that doses of 150, 300, or 600mg every 6 months or 300mg every 3 months, were able to decrease blood pressure at three and six months compared with placebo. The authors say this suggests that the drug could effectively treat high blood pressure with injections two or four times a year.

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Organisation/s: The University of Chicago, USA
Funder: The trial was funded by Alnylam Pharmaceuticals. Medical writing support was provided by PharmaGenesis Cardiff, UK and was funded by Alnylam Pharmaceuticals, Cambridge, MA, USA, in accordance with Good Publication Practice (GPP 2022) guidelines (www.ismpp.org/ gpp-2022)
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