Taking a different booster to your original vaccine may boost your antibody response

Embargoed until: Publicly released: 2022-01-27 09:00

International

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The antibody response after a booster appears to be stronger if the booster is a different vaccine to the first and second dose, according to international research. The team tested three booster shots, Pfizer, Moderna and Johnson & Johnson (similar to AstraZeneca) with about 150 participants receiving each booster. All combinations boosted neutralising antibodies, the researchers say, with a stronger response from those who mixed and matched their vaccines. T cell responses also increased for every group except those who had Johnson & Johnson only.

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Research Massachusetts Medical Society, Web page The URL will go live after the embargo ends

Journal/
conference: New England Journal of Medicine

Research:Paper

Organisation/s: Baylor College of Medicine, USA

Funder: Funded by the National Institute of Allergy and Infectious Diseases; DMID 21-0012 ClinicalTrials.gov number, NCT04889209.)

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