Concerns about AI health-prediction models trained on unreliable datasets

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Australia; QLD
Photo by Kurt Z via Unsplash.
Photo by Kurt Z via Unsplash.

Some AI models designed to predict stroke and diabetes risk may be based on datasets whose origins cannot be verified, according to new research.

News release

From: Queensland University of Technology (QUT)

Some AI models designed to predict stroke and diabetes risk may be based on datasets whose origins cannot be verified, according to new research.

The study, published in BMC Medicine and led by researchers at QUT and the Australian Centre for Health Services Innovation (AusHSI), examined two widely downloaded health datasets hosted on Kaggle, an online platform for sharing datasets and machine-learning resources, marketed as “the world’s AI proving ground”.

The datasets were found to have been used in 125 peer‑reviewed studies, despite providing almost no information about where the data came from, how it was collected or whether it represented real patients.

Lead author Alexander Gibson, from the QUT School of Public Health and Social Work and AusHSI, said the team was shocked by what they found.

“It was an enormous surprise to come across something like this,” Mr Gibson said.

“These datasets exhibit unusual patterns that raise serious questions about their authenticity and suitability for clinical research.”

Three prediction models based on the data had evidence of use in clinical practice, one model was cited in a medical device patent, and the models were cited in 86 review articles.

The study assessed the datasets using the internationally recognised TRIPOD+AI reporting framework and found that they scored 0 out of 9 on essential data‑provenance criteria.

Mr Gibson said this should be a red flag for journals, developers and clinicians.

“Prediction models built on data of unknown provenance have no place in clinical decision-making. Without trustworthy data, the outputs are unreliable and risk misleading clinicians and harming patients,” he said.

The authors said that journals, funders and data repositories must strengthen requirements for data‑source disclosure.

They also recommended that the two Kaggle datasets be removed to prevent further misuse.

Seven articles using these datasets have been retracted from journals for being unreliable. The results of study have also updated the Collection of Open Science Integrity Guides.

Mr Gibson said the issue reflects a broader challenge as AI tools proliferate in health care.

“We’re seeing fast‑churn research built on datasets that look scientific but lack the most basic transparency,” he said.

“Without stronger safeguards, unreliable models will continue to make their way into the literature, and potentially into practice.”

The study also included QUT researchers Professor Adrian Barnett and Associate Professor Nicole White.

Read the full study, Evidence of Unreliable Data and Poor Data Provenance in Clinical Prediction Model Research and Clinical Practice, published in BMC Medicine, online.

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QUT Research Team
QUT Research Team
Journal/
conference:
BMC Medicine
Research:Paper
Organisation/s: Queensland University of Technology (QUT)
Funder: This research was supported by an Australian Government Research Training Program Scholarship doi.org/10.82133/C42F-K220 for author ADG. GSC is funded by an MRC-NIHR Better Methods Better Research grant (MR/Z503873/1). GSC is funded by the National Institute for Health and Care Research (NIHR) Birmingham Biomedical Research Centre at the University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham. GSC is a National Institute for Health and Care Research (NIHR) Senior Investigator. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care.
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