Some drugs used to treat COVID-19 have dangerous interactions with others

Embargoed until: Publicly released: 2022-04-20 01:00

International

Corona_virus_Covid-19_FC By HFCM Communicatie - Own work, CC BY-SA 4.0

Italian scientists looked at past research to investigate whether any drugs used to treat COVID-19 have dangerous interactions with other COVID-19 drugs, or with medications for other conditions. In the previous studies, including a total of 1,297 patients, the team identified 115 adverse interactions between different drugs in patients being treated for COVID-19. The drugs most involved were lopinavir and ritonavir. Using drug interaction checkers could have identified at least some of these adverse reactions before they occurred, the scientists say, potentially saving lives. Further research should investigate these interactions in more detail, the researchers conclude.

Media release

From: JAMA

Identifying Drug Interaction Adverse Events in Patients With COVID-19

What The Study Did: Researchers analyzed drug-drug interactions associated with adverse clinical outcomes and/or adverse drug reactions in patients with COVID-19 and assessed whether drug interaction checkers, tools used to identify potential drug-drug interactions, are helpful in identifying such events.

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Journal/
conference: JAMA Network Open

Research:Paper

Organisation/s: University of Salerno, Italy

Funder: No information provided.

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