Snakebites may kill far more people every year than we thought

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International scientists estimated the number of deaths from venomous snakebites annually, and say there may be around 2.1 million snakebites, leading to at least 274,000 deaths, around the world every year. The team reviewed the existing evidence on snakebites in 79 countries, and used the data to create a computer model, allowing them to reach low and high estimates of global snakebite burden. This suggested between 2.1 and 7 million people are bitten each year, and that annual deaths range from 274,000 to 513,000 people, with low-income countries the worst affected. The findings suggest previous estimates of snakebites and related deaths were severe underestimations, the authors say, adding that even their study probably underestimates the impact because data were limited.

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From: PLOS

Global snakebite envenoming and mortality incidence is higher than previously reported

Study suggests at least 2.1 million envenomings, leading to at least 274,000 deaths annually

Venomous snake bites can cause illness, disability and death in tropical and subtropical regions. A study published on August 25th in PLOS Medicine by Dileepa Ediriweera and Anuradhani Kasturuiratne at the Liverpool School of Tropical Medicine, UK, and the University of Kelaniya, Sri Lanka, and colleagues suggests that the incidence of snake envenoming and snakebite mortality is much higher than previously estimated.

Snake envenoming disproportionately affects rural communities of low socioeconomic status. However, lack of data has inhibited accurate estimations of global snakebite burden. In order to calculate a range estimate for annual global snake envenoming, researchers reviewed literature on snakebites occurring in 79 countries published between January 2007 and March 2025. The researchers then developed geostatistical models based on the data inputs from their review of snake envenoming and mortality. Low and high estimates of global snakebite burden were calculated that produced individual-country estimates.

The study estimated that between 2.1-7 million people experience snake envenoming each year, and that annual mortality ranges from 274,000 to 513,000 people. Low-income countries exhibit the highest incidence and mortality rates, with sub-Saharan Africa accounting for 45% of global envenomings and deaths. The study was limited by the availability and quality of data, however, the limited data likely underreports the number of snake envenoming incidents.

According to the authors, “Our study suggests that previous burden estimates may have substantially underestimated the scale of the problem. These findings highlight the need for improved prevention, surveillance, access to antivenom and clinical care, particularly in the most affected regions. We hope our updated estimates help governments and international organisations prioritise resources and monitor progress towards reducing the burden of snakebite”.

The authors add, “Snake envenoming is a far greater global crisis than previously recognised. Our findings establish the critical baseline needed to scale up clinical care and treatment access in low-income regions across sub-Saharan Africa and Asia.

Multimedia

Map of the estimated global mortality of snake envenoming (High estimate)
Map of the estimated global mortality of snake envenoming (High estimate)

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PLOS Medicine
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Organisation/s: Liverpool School of Tropical Medicine, UK
Funder: This work was supported by the Medical Research Council [MR/P024513/1]. The grant was obtained by TI, KAM, HJdS, PJD, and DGL.
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