Recent pregnancy increases chances of breast cancer especially for women in high risk groups

Embargoed until: Publicly released: 2024-08-27 01:00

Australia; NSW; VIC

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Women who have had a recent pregnancy are at a higher risk of developing breast cancer than women who have never given birth, and the risk is even greater for women with a family history of breast cancer or a genetic predisposition to breast cancer, according to Australian and international research. The study of more than 17,000 women found that the risk of breast cancer after pregnancy is especially great in women with a family history of breast cancer or a genetic predisposition to breast cancer. The authors say future studies are needed to assess the clinical implications for this at-risk group.

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Journal/
conference: JAMA Network Open

Research:Paper

Organisation/s: The University of New South Wales, The University of Melbourne, Columbia University Irving Medical Center, USA

Funder: The 6 sites of the Breast Cancer Family Registry were supported by grant No. U01 CA164920 from the US National Cancer Institute. This work was also supported by grants to the Kathleen Cuningham Foundation Consortium for research into Familial Breast Cancer (KCF) and the KCF Follow-Up Study from Cancer Australia (grant Nos. 809195 and 1100868); the Australian National Breast Cancer Foundation (grant No. IF 17 kConFab); the National Health and Medical Research Council (grant No. 454508, 288704, and 145684); the US NIH (grant No. R01CA159868); the Queensland Cancer Fund; the Cancer Councils of New SouthWales, Victoria, Tasmania and South Australia; and the Cancer Foundation ofWestern Australia. Dr McDonald is also supported by the US National Cancer Institute (grant No. R01CA267897)

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