Once-a-month drug could help treat obesity

Embargoed until: Publicly released: 2025-06-24 10:39

Australia; International; VIC

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A new obesity drug, which can be given once a month, can reduce body weight by as much as 16% over a year, according to an early-stage clinical trial in people with diabetes and obesity. The drug, maridebart cafraglutide (known as MariTide) targets a combination of the pathway targeted with drugs such as Ozempic and another pathway involved in insulin release. Gastrointestinal side effects were also common with maridebart cafraglutide, although they were less frequent at lower doses and when the dose was slowly increased over time.